Albendazole
CAS: | 54965-21-8 |
Application: | Albendazole is a broad-spectrum anthelmintic agent widely used in veterinary medicine to manage parasitic infections in livestock, including cattle, sheep, goats, and poultry. |
Appearance: | White to off-white crystalline powder. |
Purity: | ≥98% |
Solubility: | Practically insoluble in water; slightly soluble in ethanol and chloroform. This solubility profile allows for versatile formulation options in veterinary applications, including oral suspensions, feed additives, and drenches. |
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Product Description
Albendazole is a broad-spectrum anthelmintic agent commonly used in veterinary medicine to treat a wide variety of internal parasites in livestock, including gastrointestinal worms and liver flukes. It enhances animal health and productivity by effectively controlling these parasites. Albendazole is particularly valued in the livestock industry for its efficacy in managing parasitic infections, supporting optimal growth and productivity in intensive farming environments.
1. Name and Synonyms
The product is officially named Albendazole and is widely recognized by this name in veterinary and pharmaceutical contexts. This standardized naming ensures clear identification across various applications.
2. Chemical Identification
Albendazole is identified by the CAS number 54965-21-8, serving as a unique identifier within the veterinary pharmaceutical industry. This CAS number supports accurate tracking in research, production, and quality control processes.
3. Appearance and Physical Properties
Albendazole typically appears as a white to off-white crystalline powder. This physical property aids in product identification and quality control during manufacturing and distribution.
4. Purity and Solubility
Albendazole has a high purity level of ≥ 98%, ensuring reliable performance in veterinary applications. It is practically insoluble in water but slightly soluble in organic solvents such as ethanol and chloroform, allowing for flexible formulation options, including oral suspensions and feed additives.
5. Molecular Structure
The molecular formula of Albendazole is C₁₂H₁₅N₃O₂S, with a molecular weight of approximately 265.33 g/mol. Its structure enables it to interfere with energy metabolism in parasites, providing effective control over a range of internal parasites, making it essential for managing infections in livestock.
1. Type and Mechanism of Action
Albendazole is a benzimidazole-based anthelmintic widely used in veterinary medicine to treat parasitic infections in livestock. It works by disrupting the energy metabolism of parasites through binding to beta-tubulin in parasite cells. This binding prevents the formation of microtubules, essential for cell structure and nutrient uptake, leading to the death of the parasite. This targeted mechanism makes Albendazole highly effective against a broad spectrum of parasites, providing reliable parasite control in various livestock species.
2. Spectrum of Activity
2.1 Gastrointestinal Parasites (Endoparasites)
Albendazole is effective against a wide range of gastrointestinal parasites, including roundworms (such as Haemonchus, Ostertagia, and Cooperia species), tapeworms, and whipworms. These parasites are common in livestock like cattle, sheep, and goats, and can significantly reduce productivity by impairing nutrient absorption and animal health. Albendazole’s effectiveness against these gastrointestinal parasites makes it an essential tool for managing parasitic loads, particularly in grazing livestock exposed to frequent parasite infestation.
2.2 Liver Flukes
Albendazole is also potent against liver flukes, specifically Fasciola hepatica, which affects cattle, sheep, and goats. Liver fluke infestations can cause significant damage to liver tissue, affecting an animal’s growth, milk production, and overall health. By controlling liver flukes, Albendazole helps maintain better health and productivity in livestock, reducing losses associated with liver fluke infections.
2.3 Lungworms
Albendazole has demonstrated efficacy against certain lungworms, such as Dictyocaulus species, that affect cattle and other grazing animals. Lungworms can cause respiratory distress and reduce feed efficiency in infected animals. Albendazole’s action against lungworms supports respiratory health, enhancing livestock performance and overall welfare.
3. Comparison of Anthelmintic Activity
Albendazole is valued for its broad-spectrum efficacy against various internal parasites, including gastrointestinal worms, liver flukes, and lungworms. Compared to other anthelmintic agents, Albendazole offers reliable and sustained effects, allowing for effective parasite management with fewer treatments. Its multi-target action reduces the likelihood of parasite resistance development and minimizes the need for frequent re-treatment, helping to maintain productivity and health in livestock herds.
4. Application Fields
Albendazole is widely used in veterinary applications:
•Veterinary Use: In livestock, Albendazole is primarily used for the treatment and prevention of parasitic infections, enhancing animal health, productivity, and welfare. It is particularly valuable in cattle, sheep, goats, and other grazing animals, where parasite control is crucial for maintaining growth rates, reproductive performance, and feed efficiency. Albendazole is commonly administered in oral or feed-based formulations, providing versatile and effective treatment options across different livestock types.
Albendazole’s broad-spectrum action, cost-effectiveness, and safety make it an indispensable tool in veterinary medicine for parasite management, supporting the health and productivity of livestock in intensive and extensive farming systems.
1. Shelf Life
Albendazole has a shelf life of 2 years when stored under recommended conditions. During this period, the product maintains its quality, potency, and stability, ensuring consistent efficacy in veterinary applications.
2. Testing Indicators and Standards
2.1 Appearance
Albendazole should appear as a white to off-white crystalline powder. Any noticeable deviation from this appearance may indicate potential quality concerns, serving as an essential quality control measure.
2.2 Identification
The identity of Albendazole is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC). These tests verify retention time and other chemical properties to ensure product purity and authenticity.
2.3 pH Value
The pH of a 1% solution of Albendazole in water (when required) should be within the specified range outlined in product standards. Maintaining this pH range is crucial for stability and optimal biological activity in veterinary applications.
2.4 Specific Absorbance
At 290 nm, the specific absorbance of Albendazole should meet the required range to confirm product purity and compliance with quality standards.
2.5 Light Absorbing Impurities
Impurities that absorb light at 400 nm should be controlled within specified limits. Managing these impurities ensures Albendazole’s stability and consistent performance over time.
2.6 Related Substances Content
Strict limits are set for related substances, with total impurities not exceeding 1.5%. This control ensures high purity and effectiveness, supporting Albendazole’s reliable anthelmintic action.
2.7 Heavy Metals Content
The heavy metals content in Albendazole should not exceed 10 ppm. Maintaining low heavy metal levels is essential for product safety, minimizing potential health risks in veterinary use.
2.8 Water Content
Water content should be controlled between 0.5% and 1.0%. Proper moisture levels are crucial for preserving the stability and quality of Albendazole, preventing degradation over time.
2.9 Residue on Ignition (Ash Content)
The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels indicate high product purity, reflecting minimal unwanted inorganic contaminants.
2.10 Content Determination
The active content of Albendazole should fall between 98.0% and 102.0%. Meeting this specification ensures consistent efficacy in veterinary applications, providing reliable anthelmintic action against a broad range of parasites in livestock.
1. Packaging
Albendazole is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging safeguards the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Albendazole during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and facilitating efficient inventory management.
2. Transportation Modes
2.1 Express Shipping
For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These reliable carriers provide quick delivery to meet urgent customer needs while maintaining product integrity throughout transit.
2.2 Air and Sea Freight
For bulk orders, we provide both air and sea freight options to accommodate different customer requirements. Air freight offers faster delivery for larger quantities but may incur higher costs. Sea freight is a more economical choice for larger shipments, although it involves a longer transit time. Customers can select the transportation method that best fits their order size, budget, and delivery timeline.
3. Delivery Time
Once payment is received, Albendazole orders are typically processed and dispatched within 2–3 business days. This quick turnaround allows us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.
1. GMP Compliance
Our facility strictly adheres to Good Manufacturing Practice (GMP) standards, ensuring high-quality production processes and consistent product quality for Albendazole. This certification guarantees that each batch meets rigorous industry standards for safety, efficacy, and reliability, supporting effective use in veterinary applications.
2. ISO Certification
Shandong Hope Biotech is ISO 9001 certified, reflecting our commitment to quality management and continuous improvement. This certification underscores our dedication to maintaining high standards in the production of veterinary products, including Albendazole, and assures customers of our reliable and controlled manufacturing practices.
3. Regulatory Approval for Veterinary Use
Albendazole is produced with full regulatory approval for use in the veterinary sector, meeting all necessary certifications and standards required for antiparasitic agents in animal health. This compliance ensures the product’s safety, quality, and efficacy when administered to livestock, making it suitable for various veterinary applications.
4. Third-Party Testing
Each batch of Albendazole undergoes independent third-party testing to confirm its purity, potency, and safety. We provide a Certificate of Analysis (CoA) upon request, offering transparency and reinforcing our commitment to stringent quality assurance for our customers.
5. Environmental and Safety Standards
Our production processes for Albendazole comply with strict environmental and safety regulations. We prioritize sustainable manufacturing practices that minimize environmental impact, ensure worker safety, and meet industry-leading environmental and safety standards, underscoring our commitment to responsible and ethical production.
Q1: How can I place an order for Albendazole?
A: To place an order, please reach out to our customer service team directly through any of the following methods:
•WeChat: +86-18663729963, +86-13589106478
•Skype: sunnylee886
•Email: maggie@hope-biotech.com, sunny@hope-biotech.com
•Mobile: +86-18663729963, +86-13589106478
Our team is ready to assist you with the ordering process and address any questions you may have.
Q2: What is the minimum order quantity (MOQ) for Albendazole?
A: Our standard MOQ for Albendazole is 1 kg. However, if you need a different quantity, please contact us, and we will do our best to accommodate your specific requirements.
Q3: What certifications does your company hold for Albendazole?
A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and high manufacturing standards. We follow these certifications to provide high-quality, safe, and effective Albendazole suitable for veterinary applications.
Q4: What is Albendazole used for in veterinary medicine?
A: Albendazole is a broad-spectrum anthelmintic used to treat various parasitic infections in livestock, including gastrointestinal worms, lungworms, liver flukes, and tapeworms. It is effective for cattle, sheep, goats, pigs, and even poultry, supporting overall animal health and productivity.
Q5: Can Albendazole be used in dairy animals?
A: Yes, Albendazole can be used in dairy animals, but it is essential to follow withdrawal periods before milk is used for human consumption. Always consult with a veterinarian for specific dosage and withdrawal guidance for dairy animals.
Q6: How is Albendazole administered to livestock?
A: Albendazole can be administered orally, typically in the form of a suspension, drench, or bolus, depending on the specific requirements of the livestock and the type of parasites being targeted. Proper dosage should be determined by a veterinarian based on the animal’s weight and health conditions.
Q7: What is the storage condition for Albendazole?
A: Albendazole should be stored in a cool, dry place, away from direct sunlight and moisture. It should be kept at temperatures between 2°C and 8°C to maintain its stability and effectiveness throughout its shelf life.
Q8: What is the shelf life of Albendazole?
A: Albendazole has a shelf life of 2 years if stored under recommended conditions. Maintaining the appropriate storage conditions helps ensure the product’s potency and efficacy throughout its shelf life.
Q9: Is Albendazole effective against liver flukes?
A: Yes, Albendazole is effective against liver flukes, particularly in cattle and sheep. It helps manage liver fluke infestations, which can impact productivity and overall health in livestock.
Q10: Why choose Shandong Hope Biotech for Albendazole?
A: Shandong Hope Biotech is a trusted supplier of veterinary-grade Albendazole, offering high purity, strict quality control, and reliable customer service. With certifications such as GMP and ISO 9001, we ensure that every batch meets industry standards for efficacy and safety, making us a preferred choice for veterinarians and livestock producers worldwide.