1. Name and Synonyms

The product is officially named Gentamycin Sulfate, and it is widely recognized in veterinary and pharmaceutical applications. This name ensures ease of identification across clinical and research environments.

2. Chemical Identification

Gentamycin Sulfate is identified by the CAS number 1405-41-0, which serves as a unique identifier in veterinary and pharmaceutical fields. This CAS number helps ensure accuracy in research, production, and quality control processes.

3. Appearance and Physical Properties

Gentamycin Sulfate typically appears as a white or almost white crystalline powder. This physical property aids in product identification and supports quality control during manufacturing and distribution.

4. Purity and Solubility

The product has a high purity level of ≥ 95%, ensuring its effectiveness in veterinary applications. Gentamycin Sulfate is freely soluble in water and sparingly soluble in ethanol, allowing for versatile formulation options in veterinary treatments.

5. Molecular Structure

The molecular formula of Gentamycin Sulfate is C₁₈H₃₈N₄O₁₀ · H₂SO₄ with a molecular weight of approximately 575.6 g/mol. This structure underpins its mechanism of action, which involves inhibiting bacterial protein synthesis, making it effective against a range of bacterial pathogens in livestock.

1. Antibiotic Type

Gentamycin Sulfate belongs to the aminoglycoside class of antibiotics. Aminoglycosides are broad-spectrum antibiotics particularly effective against Gram-negative bacteria. They exert their antibacterial effect by binding to the 30S ribosomal subunit of bacteria, disrupting protein synthesis and causing bacterial cell death. This mechanism makes Gentamycin Sulfate highly effective for treating a variety of serious infections in livestock, particularly respiratory and systemic infections.

2. Antibacterial Spectrum

2.1 Gram-Negative Bacteria

Gentamycin Sulfate is highly effective against a broad range of Gram-negative bacteria, including Escherichia coli, Salmonella spp., Klebsiella pneumoniae, and Pasteurella multocida. These pathogens are common causes of respiratory, urinary, and systemic infections in livestock. Gentamycin Sulfate’s effectiveness against these bacteria makes it a key treatment option for managing infections in cattle, poultry, and swine, improving animal health and productivity.

2.2 Limited Activity on Gram-Positive Bacteria

While Gentamycin Sulfate is primarily effective against Gram-negative bacteria, it also has activity against certain Gram-positive bacteria, such as Staphylococcus aureus. Staphylococcus aureus can lead to skin, wound, and soft tissue infections. However, Gentamycin is generally less effective against a wide range of Gram-positive bacteria compared to Gram-negative ones, making it more targeted in its applications.

2.3 Other Microorganisms

Gentamycin Sulfate also shows activity against certain mycoplasmas, which are common respiratory pathogens in livestock and poultry. Its ability to target both mycoplasmas and Gram-negative bacteria extends its utility in treating respiratory diseases in situations where multiple pathogens are present.

3. Comparison of Antibacterial Activity

Gentamycin Sulfate is notable for its strong action against Gram-negative bacteria, providing rapid bacterial inhibition. Its bactericidal effect is valuable for serious infections where immediate bacterial eradication is needed. Compared to other antibiotics, Gentamycin Sulfate’s broad-spectrum activity and high potency make it an effective choice for treating mixed infections in livestock, where Gram-negative bacteria are prevalent.

4. Application Fields

Gentamycin Sulfate is widely used in veterinary medicine, especially for treating respiratory, urinary, and systemic infections in livestock such as poultry, swine, and cattle. Its effectiveness against Gram-negative bacteria makes it particularly valuable in managing outbreaks that threaten animal health and productivity. Due to its broad-spectrum antibacterial properties and action against mycoplasmas, Gentamycin Sulfate is a versatile and essential antibiotic in intensive farming environments, helping to maintain animal welfare and ensure productivity in animal husbandry.

1. Shelf Life

Gentamycin Sulfate has a shelf life of 2 years when stored under recommended conditions. During this period, the product maintains its quality, effectiveness, and stability, ensuring it delivers the intended antibacterial effects for veterinary use.

2. Testing Indicators and Standards

2.1 Appearance

Gentamycin Sulfate should appear as a white or almost white crystalline powder. Any deviation from this appearance may indicate potential quality issues and serves as a basic quality control measure.

2.2 Identification

The product is identified using various analytical methods, including High-Performance Liquid Chromatography (HPLC), which confirms the identity of Gentamycin Sulfate based on retention time (tR). Additional chemical tests verify its purity and authenticity, ensuring comprehensive quality control from multiple perspectives.

2.3 pH Value

The pH of a 1% solution of Gentamycin Sulfate in water should range between 4.5 and 6.5. Maintaining this pH range is essential for product stability and biological activity, as deviations can impact its effectiveness.

2.4 Specific Absorbance

At 280 nm, the specific absorbance of Gentamycin Sulfate should fall within the specified range to confirm quality. This measurement verifies product purity and consistency with the expected absorbance profile.

2.5 Light Absorbing Impurities

At 420 nm, light-absorbing impurities should be within set limits. Controlling these impurities helps ensure product stability and reduces potential adverse effects on its antibacterial properties.

2.6 Related Substances Content

Strict limits are placed on related substances to maintain high purity. For example, any aminoglycoside-related impurities must be kept below 1.0% to ensure the quality and effectiveness of Gentamycin Sulfate in treating infections.

2.7 Heavy Metals Content

The heavy metals content in Gentamycin Sulfate should not exceed 10 ppm. This low level of heavy metals is crucial for product safety, minimizing potential risks to animal health.

2.8 Water Content

Water content should be maintained between 1.0% and 3.0%. Excess moisture can compromise product stability and quality, so controlling it within this range ensures product consistency and prevents degradation.

2.9 Residue on Ignition (Ash Content)

The residue on ignition, or ash content, should not exceed 0.1%. This low ash content reflects high product purity, free from unwanted inorganic contaminants.

2.10 Content Determination

The active content of Gentamycin Sulfate should range between 95.0% and 102.0%, ensuring potency and effectiveness in veterinary applications. Adhering to this specification guarantees reliable antibacterial action and effectiveness in livestock.

1. Packaging

Gentamycin Sulfate is packaged in fiber drums, available in two sizes: 15 kg/drum and 25 kg/drum. This packaging method offers strong protection against environmental factors like moisture, light, and oxidation, helping to preserve the product’s stability during storage and transportation. The fiber drums are designed for easy handling, simplifying logistics and inventory management.

2. Transportation Modes

2.1 Express Shipping

For smaller or urgent orders, we provide express shipping via reputable international carriers such as DHL, TNT, FedEx, and others. These express options ensure quick and reliable delivery, meeting time-sensitive needs for our customers.

2.2 Air and Sea Freight

For bulk orders, customers can choose between air or sea freight. Air freight is faster and ideal for urgent or large orders but is relatively more expensive. Sea freight is a cost-effective option for larger shipments, although it requires a longer transit time. Customers can select the transportation method based on order size, budget, and delivery urgency.

3. Delivery Time

Upon receipt of payment, Gentamycin Sulfate orders are typically processed and shipped within 2–3 business days. This prompt turnaround helps to meet urgent customer requirements, enhancing satisfaction and trust in our dependable service.

Q1: How can I place an order for Gentamycin Sulfate?

A: You can place an order by reaching out to our online customer service team for immediate assistance. Alternatively, you can contact us via:

•Wechat: +86-18663729963, +86-13589106478

•Skype: sunnylee886

•Email: maggie@hope-biotech.com, sunny@hope-biotech.com

•Mobile: +86-18663729963, +86-13589106478

Q2: What is the minimum order quantity (MOQ) for Gentamycin Sulfate?

A: Our MOQ is 0.5 kg. If you have specific quantity requirements, please discuss them with us, and we will do our best to accommodate your needs.

Q3: What certifications does your company have for Gentamycin Sulfate?

A: Our production facility holds certifications including GMP, ISO 9001, FSC, and CEP, reflecting our commitment to high-quality and reliable manufacturing practices.

Q4: What is Gentamycin Sulfate used for?

A: Gentamycin Sulfate is an aminoglycoside antibiotic commonly used in veterinary medicine to treat respiratory, urinary, and systemic infections in livestock, particularly in poultry, swine, and cattle. It is effective against a wide range of Gram-negative bacteria and certain Gram-positive bacteria.

Q5: Is Gentamycin Sulfate safe for use in animals?

A: Yes, when used according to veterinary guidance, Gentamycin Sulfate is safe and effective for treating bacterial infections in animals. Following proper dosage instructions helps ensure the best therapeutic outcomes and minimizes potential side effects.

Q6: How does Gentamycin Sulfate work?

A: Gentamycin Sulfate works by binding to the 30S ribosomal subunit in bacteria, disrupting protein synthesis and causing bacterial cell death. This bactericidal action makes it a potent choice for treating infections caused by Gram-negative bacteria and some Gram-positive bacteria.

Q7: Can Gentamycin Sulfate be used for both poultry and livestock?

A: Yes, Gentamycin Sulfate is suitable for use in various types of livestock, including poultry, cattle, and swine. Its effectiveness against respiratory, urinary, and systemic infections makes it valuable for maintaining animal health and productivity in livestock.

Q8: How should Gentamycin Sulfate be stored?

A: Store Gentamycin Sulfate in a cool, dry place away from light and moisture to maintain stability and effectiveness. Proper storage conditions help ensure the product’s quality throughout its shelf life.

Q9: What is the recommended dosage of Gentamycin Sulfate for animals?

A: The dosage varies depending on the type of animal, infection severity, and veterinary advice. We recommend consulting a licensed veterinarian to determine the appropriate dosage for specific cases.

Q10: Can I get a Certificate of Analysis (CoA) for Gentamycin Sulfate?

A: Yes, we provide a Certificate of Analysis (CoA) for each batch of Gentamycin Sulfate. The CoA includes detailed information on purity, potency, and compliance with quality standards. It is available upon request to ensure transparency and product quality assurance.