Spectinomycin Hydrochloride
CAS: | 22189-32-8 |
Application: | Spectinomycin Hydrochloride is an aminocyclitol antibiotic used in veterinary medicine to treat respiratory and enteric infections in livestock, including poultry, swine, and cattle. It is effective against Gram-negative bacteria like Escherichia coli and Pasteurella multocida, supporting animal health in intensive farming. |
Appearance: | White to off-white crystalline powder. |
Purity: | ≥98% |
Solubility: | Freely soluble in water; slightly soluble in ethanol, making it adaptable for injectable and oral veterinary formulations. |
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Product Description
Spectinomycin Hydrochloride Hydrate is a broad-spectrum aminocyclitol antibiotic widely used in veterinary medicine for its efficacy against Gram-negative bacteria, such as Escherichia coli, Pasteurella, and Mycoplasma species. It is primarily applied in treating respiratory, enteric, and systemic infections in livestock, particularly in poultry, swine, and cattle, supporting animal health and enhancing productivity in intensive farming operations.
1. Name and Synonyms
The product is officially named Spectinomycin Hydrochloride Hydrate and is commonly referred to as Spectinomycin HCl Hydrate in veterinary applications. This name is widely recognized across veterinary and pharmaceutical fields, ensuring clear identification.
2. Chemical Identification
Spectinomycin Hydrochloride Hydrate is identified by CAS number 22189-32-8, which serves as a unique identifier in pharmaceutical and veterinary sectors. This CAS number ensures accuracy in research, production, and quality control processes.
3. Appearance and Physical Properties
Spectinomycin Hydrochloride Hydrate typically appears as a white to off-white crystalline powder. This visual characteristic assists in product identification and quality control throughout manufacturing and distribution.
4. Purity and Solubility
Spectinomycin Hydrochloride Hydrate has a high purity level of ≥98%, ensuring reliable performance in veterinary applications. It is freely soluble in water, allowing for flexibility in various veterinary formulations, including injectables and oral solutions.
5. Molecular Structure
The molecular formula of Spectinomycin Hydrochloride Hydrate is C₁₄H₂₄N₂O₇ • HCl • H₂O, with a molecular weight of approximately 398.83 g/mol. This structure supports its specific action against bacterial protein synthesis, making it an effective choice for managing bacterial infections in livestock.
1. Antibiotic Type
Spectinomycin Hydrochloride is an aminocyclitol antibiotic known for its effectiveness against Gram-negative bacteria. It works by inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing mRNA translation and bacterial growth. This mechanism makes Spectinomycin Hydrochloride particularly valuable for treating respiratory and enteric infections in livestock.
2. Antibacterial Spectrum
2.1 Gram-Negative Bacteria
Spectinomycin Hydrochloride is highly effective against a range of Gram-negative bacteria, including Escherichia coli, Pasteurella multocida, and Salmonella species. These pathogens are common causes of respiratory and gastrointestinal infections in livestock such as poultry, swine, and cattle. Spectinomycin’s targeted action against these bacteria makes it a reliable choice for managing infections that impact animal health and productivity.
2.2 Limited Activity on Gram-Positive Bacteria
Spectinomycin Hydrochloride has limited activity against Gram-positive bacteria. Its selective action on Gram-negative pathogens allows it to be used in situations where broad-spectrum coverage is not required, helping preserve beneficial flora.
2.3 Other Microorganisms
Spectinomycin Hydrochloride is also effective against certain mycoplasmas, including Mycoplasma gallisepticum and Mycoplasma hyopneumoniae, which are common respiratory pathogens in poultry and swine. This makes it a preferred treatment for respiratory infections where both Gram-negative bacteria and mycoplasmas are involved.
3. Comparison of Antibacterial Activity
Spectinomycin Hydrochloride is recognized for its focused activity on Gram-negative bacteria and certain mycoplasmas. Compared to other antibiotics, it provides a more selective approach, minimizing disruption to normal bacterial flora. This specificity makes it a valuable option for targeted therapy, especially in veterinary medicine where focused treatment is advantageous.
4. Application Fields
Spectinomycin Hydrochloride is widely used in veterinary medicine, particularly for respiratory and gastrointestinal infections in livestock, including poultry, swine, and cattle. It is effective for managing bacterial infections in intensive farming, where bacterial control is crucial to ensure animal health and productivity. Its focused antibacterial action makes Spectinomycin Hydrochloride a reliable choice in animal husbandry for both treatment and preventive applications, supporting animal welfare and farm productivity.
1. Shelf Life
Spectinomycin Hydrochloride has a shelf life of 2 years when stored in a cool, dry place, protected from light. Proper storage ensures that the product maintains its quality, potency, and stability, delivering effective antibacterial action in veterinary use.
2. Testing Indicators and Standards
2.1 Appearance
Spectinomycin Hydrochloride should appear as a white or almost white crystalline powder. Variations in appearance may indicate quality concerns, making it an essential quality control indicator.
2.2 Identification
Spectinomycin Hydrochloride is verified through High-Performance Liquid Chromatography (HPLC) and other analytical methods to confirm its chemical identity, retention time, and ensure high purity and authenticity.
2.3 pH Value
The pH of a 1% aqueous solution of Spectinomycin Hydrochloride should be between 3.5 and 5.5, which is essential for product stability and effective biological activity.
2.4 Specific Absorbance
At 280 nm, the specific absorbance of Spectinomycin Hydrochloride should fall within the prescribed range, confirming product purity and compliance with quality standards.
2.5 Light Absorbing Impurities
Impurities that absorb light at 420 nm should be controlled to meet specified limits. Managing these impurities helps ensure product stability and reliability in veterinary applications.
2.6 Related Substances Content
Strict limits are set for related substances, with total impurities kept below 1.0%. This rigorous control guarantees high purity, enhancing the efficacy of Spectinomycin Hydrochloride for treating bacterial infections.
2.7 Heavy Metals Content
Heavy metals content should not exceed 10 ppm. Low heavy metal levels are critical for product safety, minimizing potential risks to animal health.
2.8 Water Content
Water content should be controlled between 1.0% and 3.0%. Maintaining proper moisture levels preserves stability and prevents degradation during storage.
2.9 Residue on Ignition (Ash Content)
The residue on ignition (ash content) should be no more than 0.2%. Low ash levels reflect high purity, free from inorganic contaminants.
2.10 Content Determination
The active content of Spectinomycin Hydrochloride should fall within 98.0% to 102.0%. Meeting this specification ensures effective antibacterial performance in veterinary applications, providing consistent and reliable treatment for livestock infections.
1. Packaging
Spectinomycin Hydrochloride is securely packaged in fiber drums, available in standard sizes of 15 kg and 25 kg per drum. This packaging provides strong protection against environmental factors like moisture, light, and oxidation, which helps preserve the product’s stability and effectiveness during storage and transportation. The design of these drums also facilitates easy handling, optimizing logistics and inventory management.
2. Transportation Modes
2.1 Express Shipping
For smaller or urgent orders, we provide express shipping through reputable international carriers, such as DHL, TNT, and FedEx. These options ensure quick and reliable delivery, catering to time-sensitive customer requirements.
2.2 Air and Sea Freight
For bulk orders, both air and sea freight options are available. Air freight is suitable for faster delivery of large quantities, although it may incur higher costs. Sea freight offers a more economical choice for larger shipments, with a longer transit time. Customers can select the transportation method that best meets their needs based on order size, budget, and delivery urgency.
3. Delivery Time
Upon receipt of payment, Spectinomycin Hydrochloride orders are typically processed and dispatched within 2–3 business days. This quick turnaround enables us to meet urgent demands, boosting customer satisfaction and reinforcing trust in our reliable and efficient service.
1. GMP Compliance
Our facility fully complies with Good Manufacturing Practice (GMP) standards, ensuring that every batch of Spectinomycin Hydrochloride is produced with strict quality control. This GMP certification verifies that our production processes meet rigorous industry standards for safety, consistency, and effectiveness.
2. ISO Certification
Shandong Hope Biotech is ISO 9001 certified, reflecting our commitment to continuous quality improvement and excellence in quality management systems. This certification supports our dedication to producing high-quality veterinary antibiotics, including Spectinomycin Hydrochloride, and reinforces our focus on reliability and consistent product standards.
3. Veterinary Drug Certification
Spectinomycin Hydrochloride is manufactured with full regulatory approval for veterinary use, complying with all necessary standards and certifications for antibiotics in animal health. This ensures the product’s safety, quality, and efficacy when used for various veterinary applications.
4. Third-Party Testing
Each batch of Spectinomycin Hydrochloride undergoes independent third-party testing to confirm its purity, potency, and safety. We provide Certificates of Analysis (CoA) upon request, offering our customers transparency and reinforcing our commitment to stringent quality assurance practices.
5. Environmental and Safety Standards
Our manufacturing operations for Spectinomycin Hydrochloride adhere to strict environmental and safety standards. We prioritize sustainable practices that minimize environmental impact and ensure worker safety, aligning with industry-leading guidelines to promote responsible and ethical manufacturing.
Q1: How can I place an order for Spectinomycin Hydrochloride?
A: You can place an order by contacting our customer service team directly. Here are our contact options:
•WeChat: +86-18663729963, +86-13589106478
•Skype: sunnylee886
•Email: maggie@hope-biotech.com, sunny@hope-biotech.com
•Mobile: +86-18663729963, +86-13589106478
Our team will assist you promptly with the ordering process and answer any questions.
Q2: What is the minimum order quantity (MOQ) for Spectinomycin Hydrochloride?
A: Our standard MOQ for Spectinomycin Hydrochloride is 0.5 kg. However, if you need a specific quantity, please let us know, and we will work to accommodate your requirements.
Q3: What certifications does your company have for Spectinomycin Hydrochloride?
A: Our production facility holds certifications including GMP and ISO 9001, ensuring high-quality production processes and consistent product quality. We also have FSC and CEP certifications, which reflect our commitment to meeting stringent international standards for veterinary products.
Q4: What is Spectinomycin Hydrochloride used for?
A: Spectinomycin Hydrochloride is an aminocyclitol antibiotic primarily used in veterinary medicine to treat respiratory, enteric, and systemic infections caused by susceptible Gram-negative bacteria. It is commonly used in livestock, particularly in swine and poultry, to promote animal health and productivity.
Q5: Is Spectinomycin Hydrochloride safe for use in animals?
A: Yes, Spectinomycin Hydrochloride is safe for use in animals when administered under veterinary guidance and according to recommended dosage instructions. It is important to follow proper dosage guidelines to ensure the best therapeutic outcomes.
Q6: How does Spectinomycin Hydrochloride work?
A: Spectinomycin Hydrochloride works by inhibiting bacterial protein synthesis. It binds to the bacterial 30S ribosomal subunit, effectively stopping bacterial growth and replication, making it a potent treatment option for infections caused by Gram-negative bacteria.
Q7: Can Spectinomycin Hydrochloride be used for both swine and poultry?
A: Yes, Spectinomycin Hydrochloride is widely used in veterinary applications for both swine and poultry. Its broad efficacy against respiratory and enteric infections makes it suitable for multiple types of livestock.
Q8: How should Spectinomycin Hydrochloride be stored?
A: Spectinomycin Hydrochloride should be stored in a cool, dry place, away from direct light and moisture, to preserve its stability and effectiveness. Proper storage helps maintain its quality over its shelf life.
Q9: What is the recommended dosage for Spectinomycin Hydrochloride in animals?
A: The dosage of Spectinomycin Hydrochloride varies depending on the animal species, infection severity, and veterinary guidance. We recommend consulting a licensed veterinarian for precise dosage instructions for specific cases.
Q10: Can I get a Certificate of Analysis (CoA) for Spectinomycin Hydrochloride?
A: Yes, we provide a Certificate of Analysis (CoA) for each batch of Spectinomycin Hydrochloride. The CoA includes details on purity, potency, and compliance with quality standards, available upon request to ensure transparency and product quality assurance.