Ivermectin
CAS: | 70288-86-7 |
Application: | Ivermectin is a broad-spectrum antiparasitic agent widely used in veterinary medicine to treat internal and external parasites in livestock, including cattle, sheep, pigs, and horses. |
Appearance: | White to yellowish crystalline powder. |
Purity: | ≥95% |
Solubility: | Ivermectin is practically insoluble in water but is soluble in organic solvents such as methanol, ethanol, and acetone. This solubility profile makes it suitable for a variety of formulations, including injectable, oral, and topical solutions, providing versatility in veterinary applications. |
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Product Description
Ivermectin is a broad-spectrum antiparasitic agent commonly used in veterinary medicine to treat and prevent parasitic infections in livestock, including cattle, sheep, goats, and swine. It is highly effective against internal parasites like gastrointestinal nematodes and lungworms, as well as external parasites such as lice and mites. Ivermectin supports improved animal health, productivity, and welfare, making it an essential tool in managing parasitic burdens in livestock.
1. Name and Synonyms
The product is officially named Ivermectin and is widely recognized under this name across veterinary and agricultural contexts. This standardized naming ensures precise identification for various therapeutic applications.
2. Chemical Identification
Ivermectin is identified by the CAS number 70288-86-7, which serves as a unique identifier within the veterinary and pharmaceutical industries. This CAS number allows for accurate tracking in research, production, and quality control processes.
3. Appearance and Physical Properties
Ivermectin typically appears as a white to yellowish crystalline powder. This visual characteristic aids in product identification and quality control during manufacturing and distribution.
4. Purity and Solubility
Ivermectin has a high purity level of ≥95%, ensuring consistent efficacy in veterinary applications. It is practically insoluble in water but soluble in organic solvents such as methanol, ethanol, and acetone, allowing for flexible formulation options, including injectable, topical, and oral solutions.
5. Molecular Structure
The molecular formula of Ivermectin is C₄₈H₇₂O₁₄, with a molecular weight of approximately 873.1 g/mol. Its chemical structure enables it to bind selectively to glutamate-gated chloride channels in parasite nerve and muscle cells, leading to paralysis and death of the parasite. This mechanism makes Ivermectin highly effective for controlling a wide range of internal and external parasites in livestock, enhancing animal health and productivity.
1. Type and Mechanism of Action
Ivermectin is an antiparasitic agent widely used in veterinary medicine to treat a variety of internal and external parasites in livestock. It works by binding selectively to glutamate-gated chloride channels in the parasite’s nerve and muscle cells, leading to an increased flow of chloride ions and causing paralysis and eventual death of the parasite. This targeted mechanism makes Ivermectin highly effective against a wide spectrum of parasites, helping to control infestations and improve overall animal health and productivity.
2. Spectrum of Activity
2.1 Internal Parasites (Endoparasites)
Ivermectin is highly effective against various gastrointestinal and respiratory nematodes, including Haemonchus, Ostertagia, and Cooperia species. These parasites can cause severe health issues, leading to reduced growth rates and productivity in livestock. Ivermectin’s efficacy in eliminating internal parasites makes it essential for maintaining livestock health, especially in grazing systems where animals are more exposed to parasite infestations.
2.2 External Parasites (Ectoparasites)
Ivermectin is also widely used to control external parasites such as mites, lice, and some species of ticks. Its action on ectoparasites improves skin and coat health and reduces the risk of parasite-related diseases. Effective control of these parasites is crucial for animal welfare and helps prevent the spread of ectoparasitic diseases within livestock populations.
3. Comparison of Antiparasitic Activity
Ivermectin is well-regarded for its broad-spectrum activity against both internal and external parasites. Compared to other antiparasitic agents, Ivermectin provides fast-acting and prolonged effects, reducing the need for frequent treatments. Its long-lasting action and versatility in controlling various parasites make it a cost-effective choice in livestock management, supporting animal welfare and reducing parasite-induced economic losses.
4. Application Fields
Ivermectin is widely applied in veterinary settings for controlling parasitic infections in livestock, including cattle, sheep, and goats.
•Veterinary Use: Ivermectin is used to treat and prevent infections caused by nematodes, mites, and lice in livestock. Its broad-spectrum efficacy ensures comprehensive parasite control, contributing to healthier, more productive animals.
•Integrated Parasite Control: Ivermectin is often a central part of integrated parasite management programs in livestock operations, targeting both internal and external parasites and reducing the overall burden on animals. This dual-purpose approach supports sustainable livestock health and enhances productivity.
1. Shelf Life
Ivermectin has a shelf life of 2 years when stored under recommended conditions. Throughout this period, the product retains its quality, potency, and stability, ensuring effective control of parasitic infections in veterinary applications.
2. Testing Indicators and Standards
2.1 Appearance
Ivermectin should appear as a white to yellowish crystalline powder. Any deviation from this appearance may suggest quality issues, serving as a key indicator for quality control.
2.2 Identification
The identity of Ivermectin is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC). These tests ensure retention time and other chemical properties match standards, confirming product purity and authenticity.
2.3 pH Value
The pH of a 1% solution of Ivermectin in water should fall within the specified range according to product standards. Appropriate pH is essential for product stability and biological activity in veterinary applications.
2.4 Specific Absorbance
At 245 nm, the specific absorbance of Ivermectin should meet required ranges to confirm product purity and compliance with quality standards.
2.5 Light Absorbing Impurities
Impurities that absorb light at 400 nm must be controlled within specified limits to ensure stability. Managing these impurities helps maintain Ivermectin’s efficacy over time in various applications.
2.6 Related Substances Content
Strict limits are set for related substances, with total impurities not exceeding 1.0%. This measure ensures high purity and consistent performance of Ivermectin in controlling parasitic infections.
2.7 Heavy Metals Content
The heavy metals content in Ivermectin should not exceed 10 ppm. Keeping heavy metal levels low is crucial for product safety, reducing risks in veterinary use.
2.8 Water Content
Water content should be controlled between 0.5% and 2.0%. Proper moisture levels are essential for preserving the stability and quality of Ivermectin, preventing degradation over time.
2.9 Residue on Ignition (Ash Content)
The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels reflect high product purity, indicating minimal unwanted inorganic contaminants.
2.10 Content Determination
The active content of Ivermectin should range between 95.0% and 102.0%. Meeting this specification ensures consistent effectiveness in veterinary applications, providing reliable antiparasitic action against a broad range of internal and external parasites in livestock.
1. Packaging
Ivermectin is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging protects the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Ivermectin during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and facilitating efficient inventory management.
2. Transportation Modes
2.1 Express Shipping
For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These trusted carriers ensure fast delivery to meet urgent customer needs while preserving product integrity throughout transit.
2.2 Air and Sea Freight
For bulk orders, we provide both air and sea freight options to accommodate different customer requirements. Air freight offers a faster delivery option for larger quantities, though it may incur higher costs. Sea freight is a more economical choice for large shipments but requires a longer transit time. Customers can select the transportation method that best suits their order size, budget, and delivery schedule.
3. Delivery Time
Once payment is received, Ivermectin orders are typically processed and dispatched within 2–3 business days. This quick turnaround allows us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.
1. GMP Compliance
Our facility strictly adheres to Good Manufacturing Practice (GMP) standards, ensuring high-quality production processes and consistent product quality for Ivermectin. This certification guarantees that each batch meets rigorous industry standards for safety, efficacy, and reliability, supporting effective use in veterinary applications.
2. ISO Certification
Shandong Hope Biotech is ISO 9001 certified, reflecting our commitment to quality management and continuous improvement. This certification underscores our dedication to maintaining high standards in the production of veterinary products, including Ivermectin, and assures customers of our reliable and controlled manufacturing practices.
3. Regulatory Approval for Veterinary Use
Ivermectin is produced with full regulatory approval for veterinary use, meeting all necessary certifications and standards required for antiparasitic agents in animal health. This compliance ensures the product’s safety, quality, and efficacy when administered to livestock, making it suitable for a variety of veterinary applications.
4. Third-Party Testing
Each batch of Ivermectin undergoes independent third-party testing to confirm its purity, potency, and safety. We provide a Certificate of Analysis (CoA) upon request, offering transparency and reinforcing our commitment to stringent quality assurance for our customers.
5. Environmental and Safety Standards
Our production processes for Ivermectin comply with strict environmental and safety regulations. We prioritize sustainable manufacturing practices that minimize environmental impact, ensure worker safety, and meet industry-leading environmental and safety standards, underscoring our commitment to responsible and ethical production.
Q1: How can I place an order for Ivermectin?
A: To place an order, please reach out to our customer service team directly through any of the following methods:
•WeChat: +86-18663729963, +86-13589106478
•Skype: sunnylee886
•Email: maggie@hope-biotech.com, sunny@hope-biotech.com
•Mobile: +86-18663729963, +86-13589106478
Our team is available to guide you through the ordering process and address any questions you may have.
Q2: What is the minimum order quantity (MOQ) for Ivermectin?
A: Our standard MOQ for Ivermectin is 1 kg. If you require a different quantity, please contact us, and we will do our best to meet your specific needs.
Q3: What certifications does your company hold for Ivermectin?
A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and superior manufacturing practices. These certifications underscore our commitment to producing Ivermectin at the highest standards for quality, safety, and reliability in veterinary and agricultural applications.
Q4: What are the main applications of Ivermectin?
A: Ivermectin is widely used as an antiparasitic agent in veterinary medicine, effective against a range of internal and external parasites, including roundworms, lungworms, lice, and mites in livestock and pets. It helps enhance animal health, productivity, and welfare by preventing parasitic infestations.
Q5: Is Ivermectin effective against both internal and external parasites?
A: Yes, Ivermectin is effective against a wide range of both internal parasites (e.g., gastrointestinal roundworms and lungworms) and external parasites (e.g., lice and mites). Its broad-spectrum efficacy makes it a versatile solution in parasite management for animals.
Q6: How should Ivermectin be stored?
A: Ivermectin should be stored in a cool, dry place away from direct sunlight and moisture. For optimal shelf life and potency, keep it tightly sealed and store it at controlled room temperature. Avoid exposure to extreme temperatures and conditions.
Q7: Is Ivermectin safe for all animal species?
A: Ivermectin is safe for many species, including cattle, sheep, goats, swine, horses, and dogs, when administered in the correct dosages. However, it is not suitable for certain breeds of dogs, such as Collies, due to genetic sensitivity to the drug. Always consult a veterinarian for species-specific dosing guidelines.
Q8: What is the recommended shelf life of Ivermectin?
A: Ivermectin has a shelf life of approximately 2 years when stored under proper conditions. Regular quality checks are performed to ensure stability and efficacy over time.
Q9: Can Ivermectin be used in integrated parasite management programs?
A: Yes, Ivermectin is an excellent choice for integrated parasite management. Its broad-spectrum activity against multiple types of parasites makes it valuable in comprehensive parasite control strategies, reducing the burden of both internal and external infestations in livestock and pets.