Toltrazuril
CAS: | 69004-03-1 |
Application: | Toltrazuril is an antiprotozoal agent extensively used in veterinary medicine to treat coccidiosis in livestock, including poultry, swine, cattle, and sheep. |
Appearance: | White to off-white crystalline powder. |
Purity: | ≥98% |
Solubility: | Slightly soluble in water; highly soluble in organic solvents like methanol and ethanol. This solubility profile allows Toltrazuril to be formulated for various administration methods, including oral and injectable solutions for flexible veterinary applications. |
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Product Description
Toltrazuril is a powerful antiprotozoal agent widely used in veterinary medicine to treat coccidiosis in livestock, including poultry, swine, cattle, and sheep. It is highly effective in targeting coccidia parasites, such as Eimeria species, at multiple stages of their life cycle. This comprehensive action makes Toltrazuril a preferred solution for managing coccidial infections, supporting animal health, productivity, and disease prevention in farming operations.
1. Name and Synonyms
The product is officially named Toltrazuril and is commonly recognized by this name across veterinary and pharmaceutical contexts. This standardized naming ensures accurate identification for various therapeutic and veterinary applications.
2. Chemical Identification
Toltrazuril is identified by the CAS number 69004-03-1, which serves as a unique identifier within veterinary and pharmaceutical industries. This CAS number facilitates precise tracking in research, production, and quality control processes.
3. Appearance and Physical Properties
Toltrazuril typically appears as a white to light beige crystalline powder. This visual characteristic assists in product identification and quality control during manufacturing and distribution.
4. Purity and Solubility
Toltrazuril has a high purity level of ≥98%, ensuring reliable performance in veterinary applications. It is practically insoluble in water, but soluble in organic solvents such as acetone and methanol, providing flexibility in various pharmaceutical formulations.
5. Molecular Structure
The molecular formula of Toltrazuril is C₁₈H₁₄F₃N₃O₄S, with a molecular weight of approximately 425.4 g/mol. This structure allows Toltrazuril to effectively target the life cycle stages of coccidia parasites, disrupting their development and providing broad-spectrum antiprotozoal action in animal health applications.
1. Antiprotozoal Type
Toltrazuril is an antiparasitic agent specifically formulated to target coccidia protozoa in livestock. It works by inhibiting enzyme systems essential for energy metabolism within the parasite, effectively halting their growth and development. This targeted mechanism makes Toltrazuril particularly effective for treating coccidiosis in cattle, poultry, and swine, especially in intensive farming environments where parasite control is crucial for animal health and productivity.
2. Antiparasitic Spectrum
2.1 Coccidia Species
Toltrazuril is highly effective against a range of coccidia species, including Eimeria and Isospora, which are common pathogens causing coccidiosis in livestock. This parasitic infection is a major concern in poultry, swine, and cattle, as it can lead to diarrhea, weight loss, and decreased growth rates. Toltrazuril’s effectiveness against these species makes it an invaluable tool for managing coccidiosis, reducing losses associated with this disease.
2.2 Life Cycle Stages of Coccidia
Toltrazuril uniquely targets multiple stages of the coccidia lifecycle, including both asexual and sexual stages. This comprehensive action prevents the parasite from completing its life cycle, thereby reducing the likelihood of reinfection. By targeting various stages of coccidia development, Toltrazuril provides a thorough solution for coccidiosis control in livestock.
3. Comparison of Antiparasitic Activity
Toltrazuril is widely recognized for its broad-spectrum activity and ability to disrupt multiple stages of coccidia development. Unlike some other coccidiostats, Toltrazuril is capable of eliminating the parasite rather than merely inhibiting its growth. Its effectiveness over a prolonged period after administration reduces the need for frequent dosing, making it practical and efficient for use in farm settings. This prolonged action helps in reducing labor and stress on animals, which is beneficial in intensive farming operations.
4. Application Fields
Toltrazuril is widely employed in veterinary medicine for the prevention and treatment of coccidiosis in livestock, particularly in poultry, swine, and cattle. It is especially useful in managing infections in young animals, where coccidiosis can severely impact growth and productivity. Toltrazuril’s single-dose effectiveness and long-lasting action make it a preferred choice in intensive farming environments, where effective parasite control, reduced handling, and improved animal welfare are high priorities.
1. Shelf Life
Toltrazuril has a shelf life of 2 years when stored under recommended conditions. During this period, the product retains its quality, potency, and stability, ensuring consistent efficacy in veterinary applications for managing coccidiosis in livestock.
2. Testing Indicators and Standards
2.1 Appearance
Toltrazuril should appear as a white to slightly yellow crystalline powder. Any noticeable deviation from this appearance may indicate potential quality issues, serving as an essential quality control measure.
2.2 Identification
The identity of Toltrazuril is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC) and Infrared Spectroscopy (IR). These tests verify retention time and other chemical properties, ensuring product purity and authenticity.
2.3 pH Value
The pH of a 1% solution of Toltrazuril in water should be within the specified range according to product standards, typically between 6.0 and 8.0. Maintaining the correct pH range is crucial for product stability and optimal biological activity in veterinary applications.
2.4 Specific Absorbance
At 243 nm, the specific absorbance of Toltrazuril should fall within the required range, confirming product purity and compliance with quality standards.
2.5 Light Absorbing Impurities
Impurities that absorb light at 400 nm should be controlled within specified limits to ensure stability. Managing these impurities helps maintain Toltrazuril’s consistent efficacy in veterinary applications.
2.6 Related Substances Content
Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and efficacy of Toltrazuril in treating coccidiosis in livestock.
2.7 Heavy Metals Content
The heavy metals content in Toltrazuril should not exceed 10 ppm. Keeping heavy metal levels low is essential for product safety, minimizing potential risks to animal health.
2.8 Water Content
Water content should be controlled between 0.5% and 1.5%. Proper moisture levels are critical to preserving the stability and quality of Toltrazuril, preventing degradation over time.
2.9 Residue on Ignition (Ash Content)
The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels reflect high product purity, indicating minimal unwanted inorganic contaminants.
2.10 Content Determination
The active content of Toltrazuril should fall between 98.0% and 102.0%. Meeting this specification ensures consistent effectiveness in veterinary applications, providing reliable antiprotozoal action against coccidiosis in livestock.
1. Packaging
Toltrazuril is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging protects the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Toltrazuril during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and improving inventory management efficiency.
2. Transportation Modes
2.1 Express Shipping
For smaller or urgent orders, we offer express shipping through trusted international carriers, including DHL, TNT, and FedEx. These carriers provide rapid delivery to meet urgent customer needs while maintaining product integrity throughout transit.
2.2 Air and Sea Freight
For bulk orders, we offer both air and sea freight options to accommodate different customer needs. Air freight ensures faster delivery for larger quantities but may involve higher costs. Sea freight is a more economical option for larger shipments, though it requires a longer transit time. Customers can select the transportation method that best suits their order size, budget, and delivery schedule.
3. Delivery Time
Once payment is received, Toltrazuril orders are typically processed and dispatched within 2–3 business days. This prompt turnaround allows us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.
1. GMP Compliance
Our facility strictly adheres to Good Manufacturing Practice (GMP) standards, ensuring high-quality production processes and consistent product quality for Toltrazuril. This certification guarantees that each batch meets rigorous industry standards for safety, efficacy, and reliability, supporting effective use in veterinary applications.
2. ISO Certification
Shandong Hope Biotech is ISO 9001 certified, reflecting our commitment to quality management and continuous improvement. This certification underscores our dedication to maintaining high standards in the production of veterinary products, including Toltrazuril, and assures customers of our reliable and controlled manufacturing practices.
3. Veterinary Drug Certification
Toltrazuril is manufactured with full regulatory approval for veterinary use, meeting all necessary certifications and standards required for antiparasitic agents in animal health. This compliance ensures the product’s safety, quality, and efficacy when used in livestock, making it suitable for a variety of veterinary applications.
4. Third-Party Testing
Each batch of Toltrazuril undergoes independent third-party testing to confirm its purity, potency, and safety. We provide a Certificate of Analysis (CoA) upon request, offering transparency and reinforcing our commitment to stringent quality assurance for our customers.
5. Environmental and Safety Standards
Our production processes for Toltrazuril comply with strict environmental and safety regulations. We prioritize sustainable manufacturing practices that minimize environmental impact, ensure worker safety, and meet industry-leading environmental and safety standards, highlighting our commitment to responsible and ethical production.
Q1: How can I place an order for Toltrazuril?
A: To place an order, please contact our customer service team using any of the following methods:
•WeChat: +86-18663729963, +86-13589106478
•Skype: sunnylee886
•Email: maggie@hope-biotech.com, sunny@hope-biotech.com
•Mobile: +86-18663729963, +86-13589106478
Our team is ready to assist you with the ordering process and answer any questions you may have.
Q2: What is the minimum order quantity (MOQ) for Toltrazuril?
A: Our standard MOQ for Toltrazuril is 1 kg. However, if you require a different quantity, please contact us, and we will do our best to accommodate your specific needs.
Q3: What certifications does your company hold for Toltrazuril?
A: Our production facility is certified with GMP and ISO 9001 standards, ensuring stringent quality control and high manufacturing standards. These certifications reflect our commitment to producing high-quality, safe, and reliable Toltrazuril products that meet international veterinary and pharmaceutical standards.
Q4: What is Toltrazuril used for in veterinary medicine?
A: Toltrazuril is an antiparasitic agent commonly used in veterinary medicine to treat coccidiosis in livestock, including poultry, cattle, sheep, and swine. Its targeted action helps eliminate coccidia parasites effectively, promoting better health and productivity in animals.
Q5: How should Toltrazuril be stored?
A: Toltrazuril should be stored in a cool, dry place, away from direct sunlight and moisture. Proper storage conditions help maintain its efficacy and stability over time.
Q6: Can Toltrazuril be used with other medications?
A: Toltrazuril can be combined with other treatments in some cases; however, it is essential to consult a veterinarian before combining it with other medications to ensure compatibility and safe treatment for animals.
Q7: What is the recommended shelf life of Toltrazuril?
A: Toltrazuril has a shelf life of approximately 2 years when stored under recommended conditions. We conduct regular quality checks to ensure product stability and efficacy throughout its shelf life.
Q8: What forms and concentrations of Toltrazuril are available?
A: We provide Toltrazuril in various formulations to meet different veterinary needs, including powder and solution forms. For specific concentration requirements, please contact us for customization options.
Q9: Is Toltrazuril safe for all animal species?
A: Toltrazuril is commonly used in livestock such as poultry, cattle, sheep, and swine. However, appropriate dosages and suitability should be confirmed with a veterinarian to ensure safety and effectiveness for specific animal species.
Q10: How does Toltrazuril work against parasites?
A: Toltrazuril works by interfering with the energy metabolism of coccidia parasites, ultimately leading to their elimination. This targeted action makes Toltrazuril highly effective in treating coccidiosis and reducing parasite load in infected animals.