Flunixin Meglumine
CAS: | 42461-84-7 |
Application: | Flunixin Meglumine is a potent non-steroidal anti-inflammatory drug (NSAID) widely used in veterinary medicine to manage pain, inflammation, and fever in livestock and companion animals. |
Appearance: | White to off-white crystalline powder. |
Purity: | ≥98% |
Solubility: | Freely soluble in water and organic solvents such as methanol and ethanol, allowing flexibility in formulations including injectable solutions and oral suspensions for effective administration in veterinary applications. |
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Product Description
Flunixin Meglumine is a potent non-steroidal anti-inflammatory drug (NSAID) widely used in veterinary medicine to manage pain, fever, and inflammation in both livestock and companion animals. It is particularly effective for treating colic in horses, acute mastitis in cattle, and respiratory diseases in swine. Its rapid action and long-lasting effects make Flunixin Meglumine an essential choice for improving animal welfare and productivity.
1. Name and Synonyms
The product is officially named Flunixin Meglumine and is widely recognized in veterinary and pharmaceutical contexts. This standardized name ensures accurate identification for various therapeutic applications.
2. Chemical Identification
Flunixin Meglumine is identified by the CAS number 42461-84-7, serving as a unique identifier in pharmaceutical and veterinary industries. This CAS number facilitates precise tracking in research, production, and quality control processes.
3. Appearance and Physical Properties
Flunixin Meglumine typically appears as a white to off-white crystalline powder, aiding in product identification and quality assurance during manufacturing and distribution.
4. Purity and Solubility
Flunixin Meglumine has a high purity level of ≥98%, ensuring consistent efficacy in veterinary applications. It is freely soluble in water and organic solvents such as methanol and ethanol, allowing for flexible formulations, including injectable solutions and oral suspensions.
5. Molecular Structure
The molecular formula of Flunixin Meglumine is C14H11F3N2O2 • C7H17NO5, with a molecular weight of approximately 491.5 g/mol. Its chemical structure allows it to inhibit cyclooxygenase (COX) enzymes, reducing the production of prostaglandins responsible for pain, inflammation, and fever. This mechanism makes Flunixin Meglumine a trusted option for managing inflammatory and painful conditions in animals.
1. Therapeutic Type
Flunixin Meglumine is a potent non-steroidal anti-inflammatory drug (NSAID) commonly used in veterinary medicine for its analgesic (pain-relieving), antipyretic (fever-reducing), and anti-inflammatory properties. It works by inhibiting the cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins responsible for pain, inflammation, and fever. This targeted mechanism makes Flunixin Meglumine a highly effective choice for managing acute and chronic inflammatory conditions in livestock and companion animals.
2. Therapeutic Spectrum
2.1 Pain Relief
Flunixin Meglumine is highly effective in managing moderate to severe pain associated with musculoskeletal injuries, colic in horses, and surgical recovery in livestock. Its ability to provide rapid and sustained pain relief enhances animal comfort and recovery.
2.2 Fever Reduction
Flunixin Meglumine is widely used to reduce fever in animals caused by bacterial or viral infections, such as bovine respiratory disease in cattle. Its antipyretic properties promote quicker recovery and reduce complications from prolonged fever.
2.3 Anti-Inflammatory Action
Flunixin Meglumine is particularly effective in controlling inflammation associated with acute mastitis in dairy cattle, laminitis in horses, and other inflammatory conditions. By reducing swelling and inflammation, it improves overall animal health and supports productivity.
3. Comparison of Therapeutic Activity
Flunixin Meglumine is known for its rapid onset and long-lasting effects, making it an ideal choice for acute pain and inflammation management. Compared to other NSAIDs, it provides superior control of colic-related pain in horses and inflammation in livestock. Its ability to reduce pain, fever, and inflammation with a single dose enhances convenience for veterinarians and animal caregivers.
4. Application Fields
Veterinary Use: Flunixin Meglumine is extensively used in cattle, horses, and swine to manage conditions such as colic, respiratory diseases, mastitis, and endotoxemia. It is also effective in post-operative pain management and other acute inflammatory conditions in livestock.
Integrated Health Management: Flunixin Meglumine is often included in health management protocols for its role in reducing inflammation and pain during treatment of infections, surgical recovery, and chronic conditions. Its broad-spectrum efficacy and rapid action make it a vital component in improving animal welfare and productivity in veterinary practices.
1. Shelf Life
Flunixin Meglumine has a shelf life of 2 years when stored under recommended conditions. During this period, the product retains its quality, potency, and stability, ensuring consistent efficacy in veterinary and pharmaceutical applications.
2. Testing Indicators and Standards
2.1 Appearance
Flunixin Meglumine should appear as a white to off-white crystalline powder. Any deviation from this appearance may indicate potential quality concerns, serving as an essential quality control measure.
2.2 Identification
The identity of Flunixin Meglumine is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC) and Infrared Spectroscopy (IR). These tests verify retention time and other chemical properties to ensure product purity and authenticity.
2.3 pH Value
The pH of a 1% aqueous solution of Flunixin Meglumine should fall within the specified range according to product standards. Maintaining this pH range is critical for product stability and optimal biological activity.
2.4 Specific Absorbance
At 285 nm, the specific absorbance of Flunixin Meglumine should meet the required range to confirm product purity and compliance with quality standards.
2.5 Light Absorbing Impurities
Impurities that absorb light at 400 nm should be controlled within specified limits to ensure stability. Managing these impurities helps maintain Flunixin Meglumine’s efficacy and consistency over time.
2.6 Related Substances Content
Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and effectiveness of Flunixin Meglumine in managing pain, fever, and inflammation.
2.7 Heavy Metals Content
The heavy metals content in Flunixin Meglumine should not exceed 10 ppm. Keeping heavy metal levels low is essential for product safety, minimizing potential risks to animal health.
2.8 Water Content
Water content should be controlled between 0.5% and 1.5%. Proper moisture levels are critical to preserving the stability and quality of Flunixin Meglumine, preventing degradation over time.
2.9 Residue on Ignition (Ash Content)
The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels reflect high product purity, indicating minimal unwanted inorganic contaminants.
2.10 Content Determination
The active content of Flunixin Meglumine should fall between 98.0% and 102.0%. Meeting this specification ensures consistent effectiveness in treatments, providing reliable analgesic, antipyretic, and anti-inflammatory actions in veterinary and pharmaceutical applications.
1. Packaging
Flunixin Meglumine is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging protects the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Flunixin Meglumine during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and facilitating efficient inventory management.
2. Transportation Modes
2.1 Express Shipping
For smaller or urgent orders, we offer express shipping through trusted international carriers, including DHL, TNT, and FedEx. These carriers ensure rapid delivery to meet urgent customer needs while maintaining product integrity throughout transit.
2.2 Air and Sea Freight
For bulk orders, we provide both air and sea freight options to accommodate various customer needs. Air freight offers faster delivery for large quantities but may involve higher costs. Sea freight is a more economical option for larger shipments, though it requires a longer transit time. Customers can select the transportation method that best aligns with their order size, budget, and delivery timeline.
3. Delivery Time
Once payment is received, Flunixin Meglumine orders are typically processed and dispatched within 2–3 business days. This swift turnaround enables us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.
1. GMP Compliance
Our facility strictly adheres to Good Manufacturing Practice (GMP) standards, ensuring high-quality production processes and consistent product quality for Flunixin Meglumine. This certification guarantees that each batch meets rigorous industry standards for safety, efficacy, and reliability, supporting effective use in veterinary and pharmaceutical applications.
2. ISO Certification
Shandong Hope Biotech is ISO 9001 certified, demonstrating our commitment to quality management and continuous improvement. This certification reflects our dedication to maintaining high standards in the production of veterinary and pharmaceutical products, including Flunixin Meglumine, and assures customers of our reliable and controlled manufacturing practices.
3. Pharmaceutical Certifications
Flunixin Meglumine is produced with full regulatory approval for veterinary and pharmaceutical use, meeting all necessary certifications and standards required for active pharmaceutical ingredients (APIs). This compliance ensures the product’s safety, quality, and efficacy, making it suitable for a variety of therapeutic applications.
4. Third-Party Testing
Each batch of Flunixin Meglumine undergoes independent third-party testing to confirm its purity, potency, and safety. We provide a Certificate of Analysis (CoA) upon request, offering transparency and reinforcing our commitment to stringent quality assurance for our customers.
5. Environmental and Safety Standards
Our production processes for Flunixin Meglumine comply with strict environmental and safety regulations. We prioritize sustainable manufacturing practices that minimize environmental impact, ensure worker safety, and meet industry-leading environmental and safety standards, underscoring our commitment to responsible and ethical production.
Q1: How can I place an order for Flunixin Meglumine?
A: To place an order, please contact our customer service team using any of the following methods:
• WeChat: +86-18663729963, +86-13589106478
• Skype: sunnylee886
• Email: maggie@hope-biotech.com, sunny@hope-biotech.com
• Mobile: +86-18663729963, +86-13589106478
Our team is ready to assist you with the ordering process and answer any questions you may have.
Q2: What is the minimum order quantity (MOQ) for Flunixin Meglumine?
A: Our standard MOQ for Flunixin Meglumine is 1 kg. However, if you require a different quantity, please contact us, and we will do our best to meet your specific needs.
Q3: What certifications does your company hold for Flunixin Meglumine?
A: Our production facility is certified with GMP and ISO 9001, ensuring rigorous quality control and adherence to international manufacturing standards. These certifications reflect our commitment to producing Flunixin Meglumine with superior quality, safety, and reliability.
Q4: What is Flunixin Meglumine used for in veterinary medicine?
A: Flunixin Meglumine is a non-steroidal anti-inflammatory drug (NSAID) used in veterinary medicine to manage pain and inflammation. It is commonly employed to treat conditions like colic in horses, bovine respiratory disease (BRD) in cattle, and mastitis. It also reduces fever and provides relief from musculoskeletal pain.
Q5: How should Flunixin Meglumine be stored?
A: Flunixin Meglumine should be stored in a cool, dry place away from direct sunlight and moisture. Proper storage ensures the product’s stability and efficacy throughout its shelf life.
Q6: What are the available forms of Flunixin Meglumine?
A: Flunixin Meglumine is available in various forms, including injectable solutions, granules, and oral paste formulations, making it adaptable to different veterinary applications.
Q7: Can Flunixin Meglumine be used in combination with other medications?
A: While Flunixin Meglumine can be used in combination with certain medications to treat complex conditions, it is essential to consult a veterinarian before combining it with other drugs to ensure safety and effectiveness.
Q8: Is Flunixin Meglumine safe for all animal species?
A: Flunixin Meglumine is approved for use in specific animals, including horses, cattle, and pigs, when used as directed. However, it is not recommended for use in small animals like dogs and cats without veterinary guidance. Always consult a veterinarian for proper dosage and suitability for your animal.
Q9: What is the recommended shelf life of Flunixin Meglumine?
A: Flunixin Meglumine has a shelf life of 2 years when stored under recommended conditions. We ensure regular quality checks to maintain the product’s stability and efficacy throughout its shelf life.
Q10: Is Flunixin Meglumine FDA-approved?
A: Yes, Flunixin Meglumine is approved by regulatory authorities, including the FDA, for veterinary use. It is widely trusted for its safety and effectiveness in managing pain, inflammation, and fever in animals.
Product Description
Imidocarb Dipropionate is a potent antiparasitic agent widely used in veterinary medicine to treat and prevent blood-borne diseases caused by protozoan parasites such as Babesia and Anaplasma. It is highly effective in managing conditions like bovine babesiosis and anaplasmosis in cattle, as well as equine piroplasmosis, thereby supporting improved health, productivity, and welfare in livestock. Its targeted action helps control disease outbreaks, making it an essential component in livestock health management.
1. Name and Synonyms
The product is officially named Imidocarb Dipropionate and is widely recognized under this name across veterinary contexts. This standardized naming ensures precise identification for various therapeutic applications.
2. Chemical Identification
Imidocarb Dipropionate is identified by the CAS number 27885-92-3, which serves as a unique identifier within veterinary medicine. This CAS number facilitates accurate tracking in research, production, and quality control processes.
3. Appearance and Physical Properties
Imidocarb Dipropionate typically appears as a white to slightly yellow crystalline powder. This physical property assists with product identification and quality control during manufacturing and distribution.
4. Purity and Solubility
Imidocarb Dipropionate has a high purity level of ≥98%, ensuring reliable performance in veterinary applications. It is practically insoluble in water but soluble in organic solvents such as ethanol, methanol, and acetone, allowing for flexibility in injectable formulations.
5. Molecular Structure
The molecular formula of Imidocarb Dipropionate is C₁₉H₂₃N₅O₂·C₆H₁₀O₄, with a molecular weight of approximately 571.6 g/mol. Its chemical structure enables it to interfere with nucleic acid synthesis in protozoan parasites, effectively eliminating them from the host animal and providing lasting protection against infections.
1. Type and Mechanism of Action
Imidocarb Dipropionate is an antiprotozoal agent commonly used in veterinary medicine to treat blood-borne parasitic infections, particularly babesiosis and anaplasmosis in livestock. Imidocarb works by interfering with the nucleic acid synthesis of the parasite, disrupting its replication process and ultimately leading to parasite death. This targeted mechanism makes Imidocarb Dipropionate highly effective against protozoal parasites that infect red blood cells, ensuring comprehensive treatment and prevention of disease transmission in livestock.
2. Spectrum of Activity
2.1 Blood-Borne Protozoal Parasites
Imidocarb Dipropionate is especially effective against Babesia and Anaplasma species, which are protozoal pathogens that affect red blood cells in cattle, sheep, and horses. These parasites can cause severe anemia, fever, and even death if left untreated. By targeting these protozoa, Imidocarb plays a crucial role in managing and preventing outbreaks of diseases like bovine babesiosis and anaplasmosis, improving animal health and productivity.
2.2 Tick-Borne Infections
Imidocarb Dipropionate is also valuable in controlling tick-borne infections since Babesia and Anaplasma are commonly transmitted by ticks. This dual benefit of treating the infection and controlling tick-borne disease transmission makes Imidocarb an essential component in integrated parasite management programs in livestock.
3. Comparison of Antiprotozoal Activity
Imidocarb Dipropionate is recognized for its efficacy in controlling blood-borne protozoal infections, particularly in comparison to other antiprotozoal agents. Its specific action against nucleic acid synthesis in parasites makes it effective for prolonged periods, reducing the need for frequent dosing. This extended action, combined with its ability to control both Babesia and Anaplasma, enhances its value in veterinary medicine, supporting animal health and reducing economic losses in farming operations.
4. Application Fields
Imidocarb Dipropionate is widely used in veterinary medicine to manage blood-borne parasitic diseases, particularly in cattle, sheep, and horses.
•Veterinary Use: Imidocarb Dipropionate is primarily used for the treatment and prevention of Babesia and Anaplasma infections in livestock. Its targeted efficacy against these parasites helps reduce mortality, improve weight gain, and support reproductive performance, making it essential for livestock health management.
•Integrated Tick Control: Given that Babesia and Anaplasma are tick-borne pathogens, Imidocarb Dipropionate aids in integrated parasite management by controlling protozoal infections and reducing the impact of tick infestations. This dual-purpose control is valuable for reducing the spread of disease in endemic areas.
Imidocarb Dipropionate’s specificity and effectiveness make it a cornerstone in managing blood-borne parasitic diseases, particularly in regions where babesiosis and anaplasmosis are prevalent. Its benefits extend to improving livestock productivity, reducing disease transmission, and supporting sustainable farming practices.
1. Shelf Life
Imidocarb Dipropionate has a shelf life of 2 years when stored under recommended conditions. During this period, the product maintains its quality, potency, and stability, ensuring reliable efficacy in veterinary applications for treating blood-borne parasitic infections.
2. Testing Indicators and Standards
2.1 Appearance
Imidocarb Dipropionate should appear as a white to off-white crystalline powder. Any noticeable deviation from this appearance may indicate potential quality issues, serving as an important quality control measure.
2.2 Identification
The identity of Imidocarb Dipropionate is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC). These tests verify retention time and other chemical properties, ensuring product purity and authenticity.
2.3 pH Value
The pH of a 1% solution of Imidocarb Dipropionate in water should be within the specified range according to product standards. Maintaining the appropriate pH range is essential for product stability and optimal biological activity in veterinary applications.
2.4 Specific Absorbance
At 254 nm, the specific absorbance of Imidocarb Dipropionate should fall within the required range to confirm product purity and compliance with quality standards.
2.5 Light Absorbing Impurities
Impurities that absorb light at 400 nm should be controlled within specified limits to ensure stability. Managing these impurities helps maintain Imidocarb Dipropionate’s efficacy in applications over time.
2.6 Related Substances Content
Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and effectiveness, supporting reliable performance of Imidocarb Dipropionate in treating blood-borne parasitic infections.
2.7 Heavy Metals Content
The heavy metals content in Imidocarb Dipropionate should not exceed 10 ppm. Maintaining low heavy metal levels is essential for product safety, minimizing risks in veterinary applications.
2.8 Water Content
Water content should be controlled between 0.5% and 2.0%. Proper moisture levels are crucial for preserving the stability and quality of Imidocarb Dipropionate, preventing degradation during storage.
2.9 Residue on Ignition (Ash Content)
The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels reflect high product purity, indicating minimal unwanted inorganic contaminants.
2.10 Content Determination
The active content of Imidocarb Dipropionate should fall between 95.0% and 102.0%. Meeting this specification ensures consistent effectiveness in veterinary treatments, providing reliable antiprotozoal action against blood-borne parasites in livestock.
1. Packaging
Imidocarb Dipropionate is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging safeguards the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Imidocarb Dipropionate during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and making inventory management more efficient.
2. Transportation Modes
2.1 Express Shipping
For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These trusted carriers provide fast delivery to meet urgent customer needs while maintaining product integrity throughout transit.
2.2 Air and Sea Freight
For bulk orders, we provide both air and sea freight options to accommodate different customer requirements. Air freight offers a quicker delivery option for larger quantities, though it may involve higher costs. Sea freight is a more economical choice for larger shipments but requires a longer transit time. Customers can select the transportation method that best aligns with their order size, budget, and delivery schedule.
3. Delivery Time
Once payment is received, Imidocarb Dipropionate orders are typically processed and dispatched within 2–3 business days. This quick turnaround enables us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.
1. GMP Compliance
Our facility strictly adheres to Good Manufacturing Practice (GMP) standards, ensuring high-quality production processes and consistent product quality for Imidocarb Dipropionate. This certification guarantees that each batch meets rigorous industry standards for safety, efficacy, and reliability, supporting effective use in veterinary applications.
2. ISO Certification
Shandong Hope Biotech is ISO 9001 certified, reflecting our commitment to quality management and continuous improvement. This certification underscores our dedication to maintaining high standards in the production of veterinary products, including Imidocarb Dipropionate, and assures customers of our reliable and controlled manufacturing practices.
3. Regulatory Approval for Veterinary Use
Imidocarb Dipropionate is produced with full regulatory approval for veterinary use, meeting all necessary certifications and standards required for antiparasitic agents in animal health. This compliance ensures the product’s safety, quality, and efficacy when administered to livestock, making it suitable for a variety of veterinary applications.
4. Third-Party Testing
Each batch of Imidocarb Dipropionate undergoes independent third-party testing to confirm its purity, potency, and safety. We provide a Certificate of Analysis (CoA) upon request, offering transparency and reinforcing our commitment to stringent quality assurance for our customers.
5. Environmental and Safety Standards
Our production processes for Imidocarb Dipropionate comply with strict environmental and safety regulations. We prioritize sustainable manufacturing practices that minimize environmental impact, ensure worker safety, and meet industry-leading environmental and safety standards, underscoring our commitment to responsible and ethical production.
Q1: How can I place an order for Imidocarb Dipropionate?
A: To place an order, please reach out to our customer service team directly through any of the following methods:
• WeChat: +86-18663729963, +86-13589106478
• Skype: sunnylee886
• Email: maggie@hope-biotech.com, sunny@hope-biotech.com
• Mobile: +86-18663729963, +86-13589106478
Our team is here to assist you with the ordering process and to answer any questions you may have.
Q2: What is the minimum order quantity (MOQ) for Imidocarb Dipropionate?
A: Our standard MOQ for Imidocarb Dipropionate is 1 kg. If you need a different quantity, please contact us, and we will do our best to accommodate your specific requirements.
Q3: What certifications does your company hold for Imidocarb Dipropionate?
A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and superior manufacturing practices. These certifications reflect our commitment to producing Imidocarb Dipropionate at the highest standards for quality, safety, and reliability in veterinary applications.
Q4: What is Imidocarb Dipropionate primarily used for?
A: Imidocarb Dipropionate is commonly used in veterinary medicine as an antiparasitic agent to treat and prevent diseases caused by blood parasites, including babesiosis and anaplasmosis, in livestock such as cattle, horses, and dogs. It is especially effective in controlling Babesia and Anaplasma infections, improving animal health and productivity.
Q5: How is Imidocarb Dipropionate administered to animals?
A: Imidocarb Dipropionate is typically administered via subcutaneous or intramuscular injection. Dosage and administration frequency depend on the species and the specific infection being treated. It is essential to follow veterinary guidelines for safe and effective use.
Q6: Are there any side effects or precautions with Imidocarb Dipropionate?
A: Some animals may experience mild side effects, such as temporary pain or swelling at the injection site. In rare cases, other adverse reactions may occur. It is important to follow recommended dosages and consult a veterinarian before administration, especially for animals with underlying health conditions. Additionally, observe recommended withdrawal periods for livestock intended for human consumption.
Q7: What is the recommended shelf life of Imidocarb Dipropionate?
A: Imidocarb Dipropionate has a shelf life of approximately 2 years when stored under recommended conditions. For optimal stability, it should be kept in a cool, dry place, away from direct sunlight and moisture.
Q8: Can Imidocarb Dipropionate be used alongside other treatments?
A: Generally, Imidocarb Dipropionate can be used alongside other medications, but it is always advisable to consult a veterinarian before combining treatments to avoid potential interactions.