1. Name and Synonyms

The product is officially named Tulathromycin and is commonly recognized by this name across veterinary and pharmaceutical contexts. This standardized name ensures clear identification for various applications.

2. Chemical Identification

Tulathromycin is identified by the CAS number 217500-96-4, serving as a unique identifier within the veterinary and pharmaceutical industries. This CAS number aids in precise tracking in research, production, and quality control processes.

3. Appearance and Physical Properties

Tulathromycin typically appears as a white to off-white crystalline powder. This characteristic supports quality control and product identification during manufacturing and distribution.

4. Purity and Solubility

Tulathromycin has a high purity level of ≥ 98%, ensuring reliable performance in veterinary applications. It is sparingly soluble in water and more soluble in organic solvents like methanol, allowing for flexibility in injectable formulations.

5. Molecular Structure

The molecular formula of Tulathromycin is C₄₁H₇₉N₃O₁₂, with a molecular weight of approximately 806.1 g/mol. Its structure allows it to inhibit bacterial protein synthesis effectively, making Tulathromycin an optimal choice for managing respiratory infections in livestock.

1. Antibiotic Type

Tulathromycin is a macrolide antibiotic specifically designed to target respiratory pathogens in livestock. It functions by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, effectively stopping bacterial growth and replication. This targeted mechanism makes Tulathromycin particularly effective for treating respiratory infections in cattle and swine, especially in intensive farming settings where respiratory disease management is essential.

2. Antibacterial Spectrum

2.1 Gram-Negative Bacteria

Tulathromycin is highly effective against key Gram-negative respiratory pathogens, including Mannheimia haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae. These bacteria are common causes of respiratory diseases such as Bovine Respiratory Disease (BRD) in cattle and Swine Respiratory Disease (SRD) in pigs. Tulathromycin’s efficacy against these pathogens makes it an invaluable tool for managing respiratory disease in livestock.

2.2 Gram-Positive Bacteria

Although primarily targeting Gram-negative bacteria, Tulathromycin also exhibits some activity against specific Gram-positive bacteria, including Streptococcus suis, which can be involved in respiratory and systemic infections. This additional activity broadens Tulathromycin’s usefulness in treating mixed infections, providing comprehensive respiratory disease management in livestock.

2.3 Mycoplasmas

Tulathromycin is effective against Mycoplasma species, including Mycoplasma hyopneumoniae in swine and Mycoplasma bovis in cattle, both of which are known to cause chronic respiratory infections. Tulathromycin’s efficacy against Mycoplasma species is a significant advantage, as these pathogens are often resistant to many other antibiotic classes.

3. Comparison of Antibacterial Activity

Tulathromycin is known for its long-acting antibacterial effects and targeted activity against Gram-negative bacteria, certain Gram-positive bacteria, and Mycoplasma species. Unlike some antibiotics, Tulathromycin can be administered as a single-dose treatment with prolonged activity, making it practical and efficient for field use. Its extended duration of action reduces the need for frequent dosing and minimizes animal handling, which is beneficial in intensive farming where reducing stress is crucial.

4. Application Fields

Tulathromycin is widely used in veterinary medicine for the prevention and treatment of respiratory infections in livestock, particularly in cattle and swine. It is especially effective for managing diseases like Bovine Respiratory Disease (BRD) and Swine Respiratory Disease (SRD), which can greatly impact animal productivity. Tulathromycin’s single-dose efficacy and long-lasting effects make it a preferred choice in intensive farming environments, where efficient disease control, reduced handling, and improved animal welfare are high priorities.

1. Shelf Life

Tulathromycin has a shelf life of 2 years when stored under recommended conditions. During this period, the product maintains its quality, potency, and stability, ensuring consistent efficacy in veterinary applications.

2. Testing Indicators and Standards

2.1 Appearance

Tulathromycin should appear as a white to off-white crystalline powder. Any noticeable deviation from this appearance may indicate potential quality issues, serving as an important quality control parameter.

2.2 Identification

The identity of Tulathromycin is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC). These tests verify retention time and other chemical properties to ensure product purity and authenticity.

2.3 pH Value

The pH of a 1% aqueous solution of Tulathromycin should range between 6.0 and 8.0. Maintaining this pH range is essential for product stability and optimal biological activity in veterinary applications.

2.4 Specific Absorbance

At 280 nm, the specific absorbance of Tulathromycin should meet the required range to confirm product purity and compliance with quality standards.

2.5 Light Absorbing Impurities

Impurities that absorb light at 400 nm should be controlled within specified limits. Controlling these impurities helps ensure Tulathromycin’s stability and consistent performance in veterinary use.

2.6 Related Substances Content

Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and efficacy of Tulathromycin in treating respiratory infections in livestock.

2.7 Heavy Metals Content

The heavy metals content in Tulathromycin should not exceed 10 ppm. Keeping heavy metal levels low is crucial for product safety, minimizing potential risks to animal health.

2.8 Water Content

Water content should be controlled between 0.5% and 1.5%. Proper moisture levels help preserve the stability and quality of Tulathromycin, preventing degradation over time.

2.9 Residue on Ignition (Ash Content)

The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels indicate high product purity, free from unwanted inorganic contaminants.

2.10 Content Determination

The active content of Tulathromycin should fall between 98.0% and 102.0%. Meeting this specification ensures the product’s effectiveness in veterinary treatments, providing reliable antibacterial action against respiratory pathogens in livestock.

1. Packaging

Tulathromycin is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging safeguards the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Tulathromycin during storage and transportation. The fiber drums are also designed for easy handling, optimizing logistics and making inventory management more efficient.

2. Transportation Modes

2.1 Express Shipping

For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These trusted carriers ensure quick delivery to meet urgent customer needs while maintaining product integrity throughout transit.

2.2 Air and Sea Freight

For bulk orders, we provide both air and sea freight options to accommodate different customer needs. Air freight provides a faster delivery option for large quantities, though it may incur higher costs. Sea freight is a more economical choice for larger shipments, although it involves a longer transit time. Customers can select the transportation method that best meets their order size, budget, and delivery timeline.

3. Delivery Time

Once payment is received, Tulathromycin orders are typically processed and dispatched within 2–3 business days. This quick turnaround allows us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.

Q1: How can I place an order for Tulathromycin?

A: To place an order, please reach out to our customer service team directly through any of the following methods:

•WeChat: +86-18663729963, +86-13589106478

•Skype: sunnylee886

•Email: maggie@hope-biotech.com, sunny@hope-biotech.com

•Mobile: +86-18663729963, +86-13589106478

Our team will be happy to assist you with the ordering process and address any questions you may have.

Q2: What is the minimum order quantity (MOQ) for Tulathromycin?

A: Our standard MOQ for Tulathromycin is 0.5 kg. If you require a different quantity, please contact us, and we will do our best to meet your specific needs.

Q3: What certifications does your company hold for Tulathromycin?

A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and top-notch manufacturing processes. We also hold FSC and CEP certifications, underscoring our commitment to high standards in the production of Tulathromycin for quality, safety, and reliability.

Q4: What is Tulathromycin used for in veterinary medicine?

A: Tulathromycin is a macrolide antibiotic widely used to treat respiratory infections in cattle and swine. It is particularly effective against pathogens such as Mannheimia haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae, making it essential for managing Bovine Respiratory Disease (BRD) and Swine Respiratory Disease (SRD).

Q5: How does Tulathromycin work?

A: Tulathromycin works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, blocking protein production and preventing bacterial growth and replication. This mechanism makes it effective in targeting respiratory pathogens in livestock.

Q6: Can Tulathromycin be administered in a single dose?

A: Yes, Tulathromycin is known for its extended duration of action, which allows for single-dose administration. This is particularly beneficial in reducing handling stress for animals and is ideal for use in intensive farming environments.

Q7: Is Tulathromycin safe for use in livestock?

A: Tulathromycin is considered safe when administered as directed by a licensed veterinarian. It is specifically formulated for use in cattle and swine to treat respiratory infections. Proper dosing and administration guidelines should be followed to maximize effectiveness and minimize any potential side effects.

Q8: What is the shelf life of Tulathromycin?

A: Tulathromycin has a shelf life of 2 years when stored under recommended conditions. This ensures the product maintains its potency and efficacy for veterinary use throughout its shelf life.

Q9: How should Tulathromycin be stored?

A: Tulathromycin should be stored in a cool, dry place away from direct sunlight and moisture. Proper storage conditions are essential for preserving the stability and effectiveness of the product.