1. Name and Synonyms

The product is officially named Tilmicosin, commonly recognized by this name in veterinary and pharmaceutical contexts. This standardized name ensures clear identification for various applications.

2. Chemical Identification

Tilmicosin is identified by the CAS number 108050-54-0, providing a unique identifier within the veterinary and pharmaceutical industries. This CAS number facilitates precise tracking in research, production, and quality control processes.

3. Appearance and Physical Properties

Tilmicosin typically appears as a pale yellow to yellow crystalline powder. This appearance aids in quality control and product identification during manufacturing and distribution.

4. Purity and Solubility

Tilmicosin has a high purity level of ≥ 98%, ensuring effective performance in veterinary applications. It is slightly soluble in water and highly soluble in organic solvents like methanol and acetone, offering versatility in formulation for injectable and oral solutions.

5. Molecular Structure

The molecular formula of Tilmicosin is C₄₆H₈₀N₂O₁₃, with a molecular weight of approximately 869.2 g/mol. This structure enables it to inhibit bacterial protein synthesis, making Tilmicosin an effective choice for managing respiratory infections in livestock.

1. Antibiotic Type

Tilmicosin is a macrolide antibiotic specifically formulated to target respiratory pathogens in livestock. It works by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, effectively halting bacterial growth and replication. This mechanism makes Tilmicosin particularly effective in treating respiratory infections in cattle, swine, and poultry, especially in intensive farming where disease management is essential.

2. Antibacterial Spectrum

2.1 Gram-Negative Bacteria

Tilmicosin is highly effective against various Gram-negative respiratory pathogens, such as Mannheimia haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae. These bacteria are common causes of respiratory infections, including Bovine Respiratory Disease (BRD) in cattle and respiratory issues in swine. Tilmicosin’s targeted action against these pathogens makes it a valuable option for managing respiratory infections in livestock.

2.2 Gram-Positive Bacteria

Tilmicosin also demonstrates significant activity against certain Gram-positive organisms, such as Staphylococcus aureus and Streptococcus suis, which can be involved in respiratory and systemic infections. This added activity enhances Tilmicosin’s effectiveness in treating mixed bacterial infections, providing comprehensive respiratory disease management.

2.3 Mycoplasmas

Tilmicosin is effective against Mycoplasma species, such as Mycoplasma hyopneumoniae in swine and Mycoplasma bovis in cattle, which are known to cause chronic respiratory infections. The effectiveness of Tilmicosin against Mycoplasma infections is an important advantage, as these pathogens are often resistant to many other antibiotic classes.

3. Comparison of Antibacterial Activity

Tilmicosin is recognized for its long-acting antibacterial effect and targeted activity against both Gram-negative and certain Gram-positive bacteria, as well as Mycoplasma species. Unlike some other antibiotics, Tilmicosin can be administered in a single dose with prolonged action, making it practical and effective for field use. Its extended duration of activity helps minimize animal handling, which is beneficial in intensive farming settings where reducing stress is essential.

4. Application Fields

Tilmicosin is widely used in veterinary medicine for the prevention and treatment of respiratory infections in livestock, particularly in cattle, swine, and poultry. It is commonly used to manage diseases like Bovine Respiratory Disease (BRD) and respiratory issues in swine herds, which can significantly impact productivity. Tilmicosin’s single-dose efficacy and long-lasting effects make it a preferred choice in intensive farming, where efficient disease control and reduced handling are critical for animal welfare and farm productivity.

1. Shelf Life

Tilmicosin has a shelf life of 2 years when stored under recommended conditions. During this period, the product maintains its quality, potency, and stability, ensuring consistent efficacy in veterinary applications.

2. Testing Indicators and Standards

2.1 Appearance

Tilmicosin should appear as a pale yellow to yellow crystalline powder. Any noticeable deviation from this appearance may indicate potential quality issues, serving as an essential quality control parameter.

2.2 Identification

The identity of Tilmicosin is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC). These tests verify retention time and other chemical properties to ensure product purity and authenticity.

2.3 pH Value

The pH of a 1% solution of Tilmicosin in water should range between 7.0 and 9.0. Maintaining this pH range is crucial for product stability and optimal biological activity in veterinary applications.

2.4 Specific Absorbance

At 280 nm, the specific absorbance of Tilmicosin should meet the required range to confirm product purity and compliance with quality standards.

2.5 Light Absorbing Impurities

Impurities that absorb light at 400 nm should be controlled within specified limits. Controlling these impurities helps ensure Tilmicosin’s stability and consistent performance in veterinary use.

2.6 Related Substances Content

Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and efficacy of Tilmicosin for treating respiratory infections in livestock.

2.7 Heavy Metals Content

The heavy metals content in Tilmicosin should not exceed 10 ppm. Keeping heavy metal levels low is essential for product safety, minimizing potential risks to animal health.

2.8 Water Content

Water content should be controlled between 1.0% and 2.0%. Proper moisture levels help preserve the stability and quality of Tilmicosin, preventing degradation over time.

2.9 Residue on Ignition (Ash Content)

The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels indicate high product purity, free from unwanted inorganic contaminants.

2.10 Content Determination

The active content of Tilmicosin should fall between 98.0% and 102.0%. Meeting this specification ensures the product’s effectiveness in veterinary treatments, providing reliable antibacterial action against respiratory pathogens in livestock.

1. Packaging

Tilmicosin is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging protects the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Tilmicosin during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and making inventory management more efficient.

2. Transportation Modes

2.1 Express Shipping

For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These trusted carriers provide rapid delivery to meet urgent customer needs while maintaining product integrity throughout transit.

2.2 Air and Sea Freight

For bulk orders, we offer both air and sea freight options to accommodate different customer needs. Air freight provides faster delivery for large quantities but may incur higher costs. Sea freight is a more economical option for larger shipments, though it requires a longer transit time. Customers can select the transportation method that best suits their order size, budget, and delivery requirements.

3. Delivery Time

Once payment is received, Tilmicosin orders are typically processed and dispatched within 2–3 business days. This quick turnaround allows us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.

Q1: How can I place an order for Tilmicosin?

A: You can place an order by contacting our customer service team directly. Here are our contact details:

•WeChat: +86-18663729963, +86-13589106478

•Skype: sunnylee886

•Email: maggie@hope-biotech.com, sunny@hope-biotech.com

•Mobile: +86-18663729963, +86-13589106478

Our team will assist you with the ordering process and address any questions you may have.

Q2: What is the minimum order quantity (MOQ) for Tilmicosin?

A: Our standard MOQ for Tilmicosin is 0.5 kg. If you require a different quantity, please contact us, and we will do our best to accommodate your specific needs.

Q3: What certifications does your company hold for Tilmicosin?

A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and manufacturing excellence. Additionally, we hold FSC and CEP certifications, reflecting our commitment to producing Tilmicosin at the highest industry standards for quality, safety, and reliability.

Q4: What is Tilmicosin used for in veterinary medicine?

A: Tilmicosin is a macrolide antibiotic widely used in veterinary medicine for the treatment of respiratory infections in livestock, particularly in cattle, poultry, and swine. It is effective against respiratory pathogens like Mannheimia haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae, which are commonly associated with respiratory diseases.

Q5: How does Tilmicosin work?

A: Tilmicosin works by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit, effectively blocking bacterial growth and replication. This mechanism makes it particularly effective for managing respiratory infections in livestock.

Q6: Is Tilmicosin safe for use in animals?

A: Yes, when used as directed by a qualified veterinarian, Tilmicosin is safe and effective for treating respiratory infections in animals. It is essential to follow the recommended dosage and administration instructions to ensure optimal results and minimize potential side effects.

Q7: Can Tilmicosin be used in both cattle and swine?

A: Yes, Tilmicosin is suitable for use in both cattle and swine. Its efficacy against common respiratory pathogens makes it a versatile solution for managing respiratory infections across these animal species.

Q8: How should Tilmicosin be stored?

A: Tilmicosin should be stored in a cool, dry place, away from direct sunlight and moisture. Proper storage helps maintain the product’s stability and efficacy over its shelf life.

Q9: What is the shelf life of Tilmicosin?

A: Tilmicosin has a shelf life of 2 years when stored under recommended conditions. This ensures the product retains its quality, potency, and effectiveness for veterinary use.

Q10: Can I get a Certificate of Analysis (CoA) for Tilmicosin?

A: Yes, we provide a Certificate of Analysis (CoA) for each batch of Tilmicosin. The CoA includes detailed information on purity, potency, and compliance with quality standards. It is available upon request to ensure transparency and guarantee product quality.