1. Name and Synonyms

The product is officially named Afoxolaner and is recognized as a trusted ectoparasiticide in the veterinary pharmaceutical industry.

2. Chemical Identification

Afoxolaner is identified by the CAS number 1093861-60-9, ensuring precise identification for research, manufacturing, and quality control.

3. Appearance and Physical Properties

Afoxolaner typically appears as a white to off-white crystalline powder, allowing for easy identification during formulation and testing processes.

4. Purity and Solubility

•Purity: ≥98%

•Solubility: Freely soluble in organic solvents such as acetone and ethanol, with limited solubility in water, making it suitable for oral chewable formulations.

5. Molecular Structure

The molecular formula of Afoxolaner is C26H17ClF9N3O3, with a molecular weight of approximately 625.88 g/mol. Its molecular structure ensures strong efficacy against parasitic infestations.

1. Mechanism of Action

Afoxolaner selectively targets the gamma-aminobutyric acid (GABA)-gated chloride channels of parasites, disrupting their nervous systems and causing paralysis and death. It has no adverse effects on the host animal due to its selective mechanism.

2. Benefits in Veterinary Medicine

2.1 Flea and Tick Control

Afoxolaner effectively eliminates adult fleas and ticks, providing rapid relief and long-lasting protection for up to 30 days.

2.2 Broad Spectrum of Action

It covers multiple tick species, including Ixodes and Dermacentor, making it suitable for various geographic regions.

2.3 Easy Administration

Typically formulated into chewable tablets, Afoxolaner ensures high compliance due to its palatability and ease of use.

2.4 Safety Profile

Afoxolaner demonstrates a high margin of safety in dogs, including puppies, when used according to prescribed dosages.

2.5 Prevention of Tick-Borne Diseases

By killing ticks rapidly, Afoxolaner helps prevent the transmission of tick-borne diseases such as Lyme disease and babesiosis.

3. Applications

•Dogs: For flea and tick control, particularly for companion animals in both urban and rural settings.

•Veterinary Clinics: As part of a parasite control regimen to improve animal welfare.

1. GMP Compliance

Our production facility adheres to Good Manufacturing Practice (GMP) standards to ensure consistent quality and safety.

2. Analytical Testing

•Purity: Verified through HPLC and other advanced analytical methods.

•Solubility: Evaluated in multiple solvents to confirm suitability for veterinary formulations.

•Stability: Extensive testing ensures Afoxolaner retains its efficacy throughout its shelf life.

3. Certification

A Certificate of Analysis (CoA) accompanies every batch to guarantee compliance with quality and safety standards.

1. Packaging

Afoxolaner is securely packaged in 25 kg fiber drums or customized packaging to meet specific customer needs. Packaging ensures protection against light, moisture, and contamination.

2. Transportation Modes

•Express Shipping: For smaller, time-sensitive orders, we offer expedited shipping through trusted carriers.

•Air and Sea Freight: Suitable for larger bulk orders, ensuring cost-effectiveness and reliability.

3. Delivery Time

Orders are processed and dispatched within 3–5 business days after payment confirmation, guaranteeing timely delivery worldwide.

Q1: What is Afoxolaner used for?

A: Afoxolaner is used to treat and prevent flea and tick infestations in dogs, providing up to 30 days of protection with a single dose.

Q2: Is Afoxolaner safe for puppies?

A: Yes, Afoxolaner is safe for puppies over 8 weeks of age and weighing more than 2 kg, as per recommended dosages.

Q3: How is Afoxolaner administered?

A: It is typically formulated into palatable chewable tablets, making administration easy and convenient for pet owners.

Q4: Does Afoxolaner prevent tick-borne diseases?

A: Yes, by killing ticks quickly, Afoxolaner helps reduce the risk of transmission of tick-borne diseases such as Lyme disease.

Q5: What is the shelf life of Afoxolaner?

A: When stored under recommended conditions, Afoxolaner has a shelf life of up to 2 years.

Q6: Can Afoxolaner be used in cats?

A: Afoxolaner is primarily formulated and approved for use in dogs. Consult your veterinarian for feline flea and tick treatments.

Q7: How can I store Afoxolaner?

A: Store Afoxolaner in a cool, dry place, away from direct sunlight and moisture, to maintain its potency.

Q8: Is a Certificate of Analysis (CoA) provided with orders?

A: Yes, we provide a CoA with every batch of Afoxolaner to ensure quality and compliance.

Q9: How do I place an order for Afoxolaner?

A: You can contact our customer service team via email or phone to place an order or inquire about pricing and delivery.

Q10: Does your company provide technical support for Afoxolaner?

A: Yes, we offer comprehensive technical support and documentation to assist customers with product applications and formulations.