1. Name and Synonyms

The product is officially named Ceftiofur Hydrochloride and has several synonyms, including Ceftiofur HCl and Ceftiofur Monohydrochloride. These names are used in various research and application scenarios, making them essential for comprehensive understanding.

2. Chemical Identification

The CAS Number for Ceftiofur Hydrochloride is 103980-44-5. This identifier is essential in the chemical field for precise scientific research, manufacturing, and quality control purposes.

3. Appearance and Physical Properties

Ceftiofur Hydrochloride appears as a white or off-white crystalline powder. This appearance is a useful indicator for product identification and quality checks.

4. Purity and Solubility

The product has a high purity requirement of ≥95% to ensure its effectiveness and stability. It is easily soluble in water and partially soluble in ethanol (96%). Additionally, it dissolves in solutions of alkali hydroxides and carbonates, which provides versatility for various application environments.

5. Molecular Structure

The molecular formula of Ceftiofur Hydrochloride is C19H17N5O7S3Cl with a molecular weight of 545.01 g/mol. Its structure underpins its biological activity and the pharmacological effectiveness of the product.

1. Stability

Ceftiofur Hydrochloride is chemically stable under recommended storage conditions. It should be stored at room temperature, away from moisture and light, to maintain its efficacy and prevent degradation.

2. Mechanism of Action

Ceftiofur Hydrochloride works by inhibiting bacterial cell wall synthesis. As a cephalosporin antibiotic, it interferes with the formation of the peptidoglycan layer of bacterial cell walls, which is essential for their structural integrity. This results in cell lysis and the eventual death of the bacterial cell.

3. Spectrum of Activity

Ceftiofur Hydrochloride is effective against a broad range of Gram-positive and Gram-negative bacteria, making it a versatile choice in veterinary medicine. It is commonly used to treat respiratory infections, foot rot, and other bacterial infections in animals.

4. Pharmacokinetics

After administration, Ceftiofur Hydrochloride is rapidly absorbed and distributed throughout the animal’s body. It has a relatively short half-life and is excreted primarily through urine. The pharmacokinetic properties may vary depending on the species of the animal and the route of administration.

5. Safety and Toxicity

Ceftiofur Hydrochloride is generally considered safe for use in veterinary applications when used as directed. However, it is essential to adhere to the recommended dosage and usage guidelines to avoid any potential adverse reactions. Overdose or misuse may lead to antibiotic resistance or side effects in animals.

6. Storage and Handling

The product should be stored at room temperature in a well-ventilated, dry area, away from incompatible substances. Proper handling procedures must be followed to prevent accidental ingestion, inhalation, or contact with the skin and eyes.

1. Purity

Ceftiofur Hydrochloride has a minimum purity specification of ≥95%, ensuring high-quality standards for effective treatment results.

2. Assay

The assay results typically confirm the active component percentage within the specified range, ensuring consistent quality in every batch.

3. Loss on Drying

The acceptable range for loss on drying is usually kept low to maintain product stability and prevent moisture-related degradation.

4. Residual Solvents

Manufacturing of Ceftiofur Hydrochloride adheres to strict guidelines for residual solvents, following regulatory standards to ensure product safety.

5. Heavy Metals

Ceftiofur Hydrochloride complies with regulatory limits on heavy metals, ensuring it is free from harmful levels of metals like lead, arsenic, mercury, and cadmium.

6. Microbial Limits

The product is manufactured in compliance with microbiological safety standards, ensuring minimal microbial contamination and maintaining product integrity.

1. Packaging Options

Ceftiofur Hydrochloride is available in various packaging options to meet customer requirements, typically packed in sealed, moisture-resistant containers to preserve its quality during storage and transportation. Packaging sizes can vary, and bulk options are available.

2. Labeling

Each package is labeled with essential product information, including product name, CAS number, batch number, purity, and storage instructions. This labeling ensures traceability and compliance with industry standards.

3. Transportation

The product is shipped under conditions that prevent exposure to excessive heat, moisture, and light. Transportation is managed to maintain product integrity, ensuring it arrives in optimal condition.

4. Storage Conditions

Recommended storage conditions are room temperature in a dry, well-ventilated area. Avoid direct sunlight and moisture exposure to maintain stability and effectiveness.

Q1: What is the recommended dosage of Ceftiofur Hydrochloride?

A1: The dosage of Ceftiofur Hydrochloride depends on the animal species, weight, and condition being treated. Consult a veterinary professional for precise dosage guidelines.

Q2: How should Ceftiofur Hydrochloride be stored?

A2: Store the product at room temperature in a dry, well-ventilated area away from moisture and direct sunlight to maintain stability.

Q3: Is Ceftiofur Hydrochloride safe for all animals?

A3: While generally safe for veterinary use, the product should only be used under veterinary supervision, especially for sensitive species.

Q4: What are the main applications of Ceftiofur Hydrochloride?

A4: Ceftiofur Hydrochloride is commonly used to treat bacterial infections in animals, such as respiratory infections, foot rot, and other bacterial diseases.

Q5: Can Ceftiofur Hydrochloride be used in combination with other antibiotics?

A5: Combination use should only be done under veterinary advice to avoid potential drug interactions and antibiotic resistance.