Specification
The product is officially named Doxycycline Hyclate and also has several synonyms, including Doxycycline hydrochloride, Deoxytetracycline, and Deoxynivalenol. These different names may be used in different research and application scenarios, and understanding them is beneficial for a more comprehensive understanding of the product.
Its chemical identification information is clear, with a CAS number of 10592 – 13 – 9. This unique identifier in the chemical field is of great significance for scientific research, production, and quality control.
Doxycycline Hyclate appears as a yellow crystalline powder. This appearance characteristic is an important reference indicator in product identification and quality inspection.
The product has a relatively high purity requirement of ≥95%. This ensures its effectiveness and stability during use. In terms of solubility, it has unique properties. It is freely soluble in water and methanol, which enables convenient preparation and use in some application scenarios requiring aqueous or methanol solutions. However, its solubility in 96% ethanol is sparingly soluble. Additionally, it can dissolve in solutions of alkali metal hydroxides and carbonates, providing possibilities for its application in different chemical environments.
From a chemical structure perspective, its molecular formula is C22H25ClN2O8, and its molecular weight is 480.8955. The molecular structure determines the chemical properties and biological activities of the substance and plays a crucial role in understanding the mechanism of action and pharmacological characteristics of Doxycycline Hyclate.
Properties
1.Antibiotic Type
Doxycycline Hyclate belongs to the tetracycline class of antibiotics. Tetracycline antibiotics are a widely used class of antibiotics with broad-spectrum antibacterial properties. They exert their antibacterial effect by inhibiting bacterial protein synthesis and have an inhibitory effect on a variety of bacteria.
2. Antibacterial Spectrum
2.1 Gram-Positive Bacteria
It has an inhibitory effect on pneumococci, streptococci, and some other Gram-positive bacteria. Pneumococci are common pathogens causing respiratory diseases such as pneumonia, and streptococci can cause various infectious diseases such as pharyngitis and scarlet fever. Doxycycline Hyclate can inhibit these pathogens and thus play a role in treating related diseases.
It is also effective against some staphylococci, Bacillus anthracis, Bacillus tetani, Bacillus rotundus, and other Gram-positive bacteria. These bacteria can cause diseases in different environments and hosts, and the antibacterial spectrum of Doxycycline Hyclate covering them increases the breadth of its application.
2.2 Gram-Negative Bacteria
It also has an inhibitory effect on Escherichia coli, Bartonella, Salmonella, Brucella, Haemophilus, Klebsiella, and Bacillus nasalis, and other Gram-negative bacteria. Escherichia coli is a common flora in the intestine but can cause intestinal infections and other diseases under certain circumstances; Salmonella is an important pathogen causing food poisoning and intestinal infections; Brucella can cause brucellosis and other diseases. The inhibitory ability of Doxycycline Hyclate against these Gram-negative bacteria makes it valuable for treating intestinal diseases and systemic infections in livestock and poultry.
2.3 Other Microorganisms
In addition to bacteria, it also has a certain degree of inhibition on rickettsiae, mycoplasmas (such as Mycoplasma pneumoniae), and spirochetes. Rickettsiae are a class of microorganisms between bacteria and viruses and can cause diseases such as typhus; mycoplasmas are a class of microorganisms lacking cell walls and can cause infections in the respiratory tract, urogenital tract, and other parts; spirochetes can cause diseases such as syphilis. The inhibitory effect of Doxycycline Hyclate on these microorganisms further broadens its application range.
3. Comparison of Antibacterial Activity
The antibacterial activity of Doxycycline Hyclate is 2 – 10 times higher than that of hygromycin. This higher antibacterial activity may result in better efficacy in treating infectious diseases, enabling more effective inhibition of bacterial growth and reproduction and thus accelerating the recovery speed of animals.
4 Application Fields
It is a common drug used in breeding with a relatively high frequency of use. In veterinary clinical practice, it is often used to treat mycoplasma infections in poultry and respiratory diseases in pigs. Especially for the treatment of mixed infections of mycoplasma and bacteria, the effect is also very good. This is because it can simultaneously inhibit mycoplasma and a variety of bacteria, thereby comprehensively controlling the infection situation and improving the treatment effect.
Quality Control
The product has a shelf life of 2 years. During the specified shelf life, the product can maintain its quality and effectiveness, providing guidance on the storage and use of the product.
The standard requires the product to have a yellow crystalline powder appearance. This is an intuitive testing indicator, and if the product appearance does not meet the requirements, it may indicate a quality problem.
It is identified through multiple methods, including HPLC testing (high-performance liquid chromatography testing), where the retention time (tR) is used to determine the identity of the product; it also includes sulfuric acid yellow reaction and chloride reaction and other chemical identification methods. These identification methods ensure the authenticity and purity of the product from different perspectives.
The product’s pH value is required to be between 2.0 – 3.0. The pH value is an indicator of the acidity or alkalinity of a solution and may affect the stability and biological activity of the Doxycycline Hyclate solution, so it needs to be strictly controlled within the specified range.
At 349nm, the specific absorbance is required to be between 300 – 335, calculated on the anhydrous, non-ethanol substance. Absorbance is a measure of the degree of light absorption by a substance, and the requirement for specific absorbance helps to ensure the quality and purity of the product.
At 490nm, the content of light absorbing impurities is required to be no more than 0.07 (calculated on the anhydrous, non-ethanol substance). Controlling the content of light absorbing impurities can improve the quality and stability of the product and reduce the impact of impurities on product performance.
The content of various related substances is regulated. For example, the content of 6 – epidoxycycline is not more than 2.0%, the content of oxytetracycline is not more than 0.5%, and the content of 4 – epidoxycycline, 4,6 – epidoxycycline, impurity F, and any other impurities are not more than 0.5%. Strictly controlling the content of related substances can ensure the purity and quality of the product and avoid the impact of impurities on the antibacterial effect and safety of the product.
The product’s ethanol content is required to be between 4.3% – 6.0%. The control of ethanol content also has an impact on the stability and quality of the product.
The heavy metals content is required to be less than 50 ppm (parts per million). Excessive heavy metals may harm animal health, so strict control of heavy metals content is an important measure to ensure product safety.
The water content is required to be between 1.4% – 2.8%. Excessive water content may affect the stability and quality of the product, such as causing product caking and deterioration.
The sulfated Ash content is required to be no more than 0.4%. The sulfated Ash is a measure of the inorganic components in the product, and controlling its content helps to ensure the quality of the product.
Calculated on the anhydrous, non-ethanol substance, the content of C22H25CLN2O8 in the product is required to be between 95.0 – 102.0%. Content determination is a key indicator for ensuring product quality, and only products within the specified range can ensure their effectiveness and safety.
Packaging&Transportation
The product is packaged in fiber drums, with two specifications of 15kg/drum and 25kg/drum. This packaging method can effectively protect the product from external environmental influences such as moisture and oxidation, and is also convenient for product storage and transportation.
It can be transported by DHL, TNT, Fedex, etc., international well-known express services. These express services are fast and reliable and can deliver the product to customers in a relatively short time.
For large quantities of goods, air or sea transportation can be chosen. Air transportation is fast but relatively expensive; sea transportation is less expensive but takes a longer time. According to the customer’s needs and actual situation, a suitable transportation mode can be flexibly chosen.
After receiving payment, the product will be delivered within 2 – 3 days. This fast delivery time can meet the urgent needs of customers and improve customer satisfaction.
Company Certifications
1. GMP Compliance
Our facility operates in compliance with Good Manufacturing Practice (GMP) standards, ensuring high-quality production processes and consistent product quality for Doxycycline Hyclate.
2. ISO Certification
The company holds ISO 9001 certification, demonstrating our commitment to quality management standards and continuous improvement in our manufacturing practices for veterinary antibiotics.
3. Veterinary Drug Certification
Doxycycline Hyclate is produced with regulatory approval for veterinary applications, adhering to industry standards and certifications required for antibiotics used in animal health.
4. Third-Party Testing
We conduct third-party testing on each batch of Doxycycline Hyclate to ensure compliance with purity, potency, and safety standards. Certificates of Analysis (CoA) are available upon request.
5. Environmental and Safety Standards
Our manufacturing processes for Doxycycline Hyclate comply with environmental and safety regulations, ensuring responsible production practices that minimize environmental impact and uphold industry safety standards.
FAQ
Q1: How to order this product?
A: You can chat with online service directly.
You can also contact us in the following ways.
Wechat:+86-18663729963, +86-13589106478
Skype: sunnylee886
Email:maggie@hope-biotech.com
sunny@hope-biotech.com
Mobile:+86-18663729963, +86-13589106478
Q2: What’s the MOQ?
A: The MOQ is 0.5kg, you can also tell us the quantity you want.
Q3: How about your company’s certification?
A: GMP, ISO, FSC, CEP etc.
Doxycycline, Doxycycline hyclate,Doxycycline hydrochloride, Deoxytetracycline,Deoxynivalenol
Doxycycline uses,Doxycycline for animal use, Doxycycline for poultry,Doxycycline manufacturer,
Doxycycline 100mg
Hot Tags: doxycycline hyclate, China, suppliers, manufacturers, factory, , Ceftiofur Sodium, Oxytetracycline Hydrochloride, Liquid Injection, Tylosin Tartrate Powder, Veterinary Antibiotic
1. Name and Synonyms
1.Antibiotic Type
1.Shelf Life
1. Packaging
1. GMP Compliance
Q1: How to order this product?
