1. Name and Synonyms

The product is officially named Erythromycin Thiocyanate, sometimes referred to as Erythromycin Thiosulfate in certain veterinary settings. This name is widely recognized in clinical and research environments, ensuring ease of identification across applications.

2. Chemical Identification

Erythromycin Thiocyanate is identified with the CAS number 7704-67-8, serving as a unique identifier in the pharmaceutical and veterinary fields. This CAS number ensures accuracy in research, production, and quality control processes.

3. Appearance and Physical Properties

Erythromycin Thiocyanate typically appears as a white or almost white crystalline powder. This appearance characteristic assists in the identification of the product and supports quality control throughout manufacturing and distribution.

4. Purity and Solubility

The product boasts a high purity level of ≥ 95%, ensuring effective results in veterinary applications. Erythromycin Thiocyanate is slightly soluble in water but more soluble in ethanol, methanol, and acetone, allowing for versatile formulation options in veterinary treatments for livestock and poultry.

5. Molecular Structure

The molecular formula of Erythromycin Thiocyanate is C₃₇H₆₇NO₁₃S with a molecular weight of approximately 767.0 g/mol. This structure underpins its mechanism of action, targeting bacterial protein synthesis, which makes it effective against a range of bacterial pathogens in livestock.

1. Antibiotic Type

Erythromycin Thiocyanate belongs to the macrolide class of antibiotics. Macrolides are effective against a range of Gram-positive bacteria and exert their antibacterial effect by inhibiting bacterial protein synthesis. They bind to the 50S ribosomal subunit of bacteria, preventing the elongation of the protein chain, which is essential for bacterial growth and replication. This mechanism makes Erythromycin Thiocyanate valuable for treating various infections in livestock, particularly respiratory and skin infections.

2. Antibacterial Spectrum

2.1 Gram-Positive Bacteria

Erythromycin Thiocyanate is highly effective against a broad range of Gram-positive bacteria, including Streptococcus spp., Staphylococcus aureus, and Corynebacterium spp. Streptococcus species are known to cause respiratory and systemic infections, while Staphylococcus aureus is associated with skin and soft tissue infections. Corynebacterium species, which can lead to skin infections, are also susceptible. The efficacy of Erythromycin Thiocyanate against these pathogens makes it a key treatment option for managing respiratory, skin, and systemic infections in livestock.

2.2 Limited Activity on Gram-Negative Bacteria

While Erythromycin Thiocyanate is primarily effective against Gram-positive bacteria, it has limited activity against Gram-negative bacteria. This selective spectrum focuses its use on infections commonly caused by Gram-positive organisms, making it well-suited for targeted applications in animal husbandry without affecting the beneficial Gram-negative flora in animals.

2.3 Other Microorganisms

Erythromycin Thiocyanate also shows activity against certain mycoplasmas (e.g., Mycoplasma gallisepticum), which lack cell walls and are common respiratory pathogens in poultry and other livestock. This effectiveness against mycoplasmas broadens the scope of Erythromycin Thiocyanate, especially for treating respiratory diseases in cases where both Gram-positive bacteria and mycoplasmas are involved.

3. Comparison of Antibacterial Activity

Erythromycin Thiocyanate is notable for its targeted activity against Gram-positive bacteria, providing strong inhibition and effective control of infections. Compared to other antibiotics, its selective focus on Gram-positive bacteria minimizes disruption to normal flora, making it a preferred choice for respiratory and skin infections in animals. Its effectiveness against mycoplasmas also gives it an edge in treating respiratory diseases where other antibiotics may be less effective.

4. Application Fields

Erythromycin Thiocyanate is widely used in veterinary medicine, especially for treating respiratory and skin infections in livestock, including poultry, swine, and cattle. It is particularly effective in managing outbreaks of bacterial infections that can negatively impact animal health and productivity. Due to its broad-spectrum activity against Gram-positive bacteria and effectiveness against mycoplasmas, Erythromycin Thiocyanate is a versatile and essential antibiotic in intensive farming environments. Its role in controlling bacterial diseases helps support animal welfare and maintain productivity in animal husbandry.

1. Shelf Life

Erythromycin Thiocyanate has a shelf life of 2 years when stored under recommended conditions. During this period, the product retains its quality, effectiveness, and stability, ensuring it delivers the intended antibacterial effects for veterinary use.

2. Testing Indicators and Standards

2.1 Appearance

Erythromycin Thiocyanate should appear as a white or almost white crystalline powder. Any deviation from this appearance may indicate potential quality issues and serves as a basic quality control measure.

2.2 Identification

The product is identified using various analytical methods, including High-Performance Liquid Chromatography (HPLC), which uses retention time (tR) to confirm the identity of Erythromycin Thiocyanate. Additional chemical tests verify its purity and authenticity, ensuring quality from multiple perspectives.

2.3 pH Value

The pH of a 1% solution of Erythromycin Thiocyanate in water should be between 7.0 and 9.0. Maintaining this pH range is essential for product stability and biological activity, as deviations can impact the product’s effectiveness.

2.4 Specific Absorbance

At 285 nm, the specific absorbance of Erythromycin Thiocyanate should meet the required range to ensure quality. This measurement confirms product purity and verifies that it aligns with the expected absorbance profile.

2.5 Light Absorbing Impurities

At 420 nm, the content of light-absorbing impurities should not exceed specified limits. Controlling these impurities helps maintain product stability and reduces the risk of adverse effects on its antibacterial activity.

2.6 Related Substances Content

Strict limits are placed on related substances to ensure high purity. For example, any macrolide-related impurities must be kept below 1.0% to maintain the quality and effectiveness of Erythromycin Thiocyanate in treating infections.

2.7 Heavy Metals Content

The heavy metals content in Erythromycin Thiocyanate should not exceed 20 ppm. This low level is critical for product safety, reducing potential risks to animal health.

2.8 Water Content

Water content should be controlled between 2.0% and 4.0%. Excess moisture can impact the stability and quality of Erythromycin Thiocyanate, so maintaining it within this range ensures product consistency and prevents degradation.

2.9 Residue on Ignition (Ash Content)

The residue on ignition, or ash content, should not exceed 0.1%. This low ash content indicates high product purity, free from unwanted inorganic contaminants.

2.10 Content Determination

The potency of Erythromycin Thiocyanate is determined based on its active content, which should range between 95.0% and 102.0%. Ensuring the active content meets this specification guarantees the product’s effectiveness in veterinary applications, providing reliable antibacterial action.

1. Packaging

Erythromycin Thiocyanate is packaged in fiber drums, available in two sizes: 15 kg/drum and 25 kg/drum. This packaging provides effective protection against moisture, light, and oxidation, ensuring the product’s stability during storage and transportation. The fiber drums are also designed for easy handling, making logistics and inventory management more efficient.

2. Transportation Modes

2.1 Express Shipping

For smaller or urgent orders, we offer express shipping through trusted international carriers like DHL, TNT, FedEx, and other reputable providers. These express options ensure quick and reliable delivery to meet the time-sensitive needs of our customers.

2.2 Air and Sea Freight

For bulk orders, air or sea freight can be selected. Air freight is ideal for faster delivery of large quantities, though it is relatively more expensive. Sea freight, on the other hand, is a cost-effective option for larger shipments but has a longer transit time. Customers can select the transportation method that best suits their needs based on the order size and required delivery timeframe.

3. Delivery Time

Upon receipt of payment, Erythromycin Thiocyanate orders are processed and shipped within 2–3 business days. This quick turnaround helps meet urgent customer needs, ensuring satisfaction and building customer trust in our reliable service.

Q1: How can I place an order for Erythromycin Thiocyanate?

A: You can place an order by reaching out to our online customer service team for immediate assistance. Alternatively, you can contact us through the following methods:

•Wechat: +86-18663729963, +86-13589106478

•Skype: sunnylee886

•Email: maggie@hope-biotech.com, sunny@hope-biotech.com

•Mobile: +86-18663729963, +86-13589106478

Q2: What is the minimum order quantity (MOQ) for Erythromycin Thiocyanate?

A: Our MOQ is 0.5 kg. However, if you have specific quantity requirements, please discuss them with us, and we’ll do our best to accommodate your needs.

Q3: What certifications does your company have for Erythromycin Thiocyanate?

A: Our production facility holds certifications including GMP, ISO 9001, FSC, and CEP, which confirm our commitment to high-quality, reliable manufacturing practices.

Q4: What is Erythromycin Thiocyanate used for?

A: Erythromycin Thiocyanate is a macrolide antibiotic commonly used in veterinary medicine to treat respiratory, skin, and systemic infections in livestock, particularly poultry and swine. It is effective against a range of Gram-positive bacteria and mycoplasmas.

Q5: Is Erythromycin Thiocyanate safe for use in animals?

A: Yes, when used according to veterinary guidance, Erythromycin Thiocyanate is safe and effective for treating bacterial infections in animals. Proper dosage instructions should be followed to maximize therapeutic outcomes and minimize any side effects.

Q6: How does Erythromycin Thiocyanate work?

A: Erythromycin Thiocyanate inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively stopping bacterial growth. This mechanism makes it a potent option for treating infections caused by Gram-positive bacteria and mycoplasmas.

Q7: Can Erythromycin Thiocyanate be used for both poultry and livestock?

A: Yes, Erythromycin Thiocyanate is suitable for use in various types of livestock, including poultry and swine. Its effectiveness against respiratory and skin infections makes it valuable in maintaining animal health and productivity.

Q8: How should Erythromycin Thiocyanate be stored?

A: Store Erythromycin Thiocyanate in a cool, dry place, away from light and moisture to maintain stability and effectiveness. Proper storage conditions ensure that the product retains its quality over its shelf life.

Q9: What is the recommended dosage of Erythromycin Thiocyanate for animals?

A: The dosage varies depending on the animal type, infection severity, and veterinarian’s advice. We recommend consulting a licensed veterinarian to determine the appropriate dosage for specific situations.

Q10: Can I get a Certificate of Analysis (CoA) for Erythromycin Thiocyanate?

A: Yes, we provide a Certificate of Analysis (CoA) for each batch of Erythromycin Thiocyanate. The CoA includes detailed information on purity, potency, and compliance with quality standards. It is available upon request for full transparency and assurance of product quality.