1. Name and Synonyms

The product is officially named Praziquantel and is widely recognized in veterinary and pharmaceutical applications. This standardized name ensures precise identification across various therapeutic contexts.

2.Chemical Identification

Praziquantel is identified by the CAS number 55268-74-1, which serves as a unique identifier in veterinary and pharmaceutical industries. This CAS number facilitates accurate tracking in research, production, and quality control processes.

3.Appearance and Physical Properties

Praziquantel typically appears as a white to off-white crystalline powder, aiding in product identification and quality control during manufacturing and distribution.

4.Purity and Solubility

Praziquantel has a high purity level of ≥98%, ensuring consistent efficacy in veterinary applications. It is sparingly soluble in water but freely soluble in organic solvents such as ethanol and acetone, providing flexibility for various formulations, including oral tablets and injectable solutions.

5.Molecular Structure

The molecular formula of Praziquantel is C₁₉H₂₄N₂O₂, with a molecular weight of approximately 312.4 g/mol. Its unique structure enables it to disrupt the cell membrane integrity of parasites, leading to paralysis and elimination from the host, making Praziquantel highly effective in treating a variety of parasitic infections in animals.

1. Antiparasitic Type

Praziquantel is a broad-spectrum antiparasitic agent specifically formulated to target parasitic worms, particularly trematodes (flukes) and cestodes (tapeworms). Its mechanism of action involves disrupting the cell membrane permeability of these parasites, leading to muscular contraction, paralysis, and death of the parasite. This targeted action makes Praziquantel highly effective for treating parasitic infections in livestock and companion animals, including cattle, sheep, dogs, and cats, where control of parasitic worms is essential.

2. Antiparasitic Spectrum

2.1 Trematodes (Flukes)

Praziquantel is highly effective against a variety of trematode species, including liver flukes such as Fasciola hepatica and blood flukes such as Schistosoma species. These flukes are responsible for significant diseases in livestock, leading to reduced productivity. Praziquantel’s efficacy against these parasites helps in managing fluke infections and promoting the overall health and productivity of livestock.

2.2 Cestodes (Tapeworms)

Praziquantel is also effective against a wide range of cestodes, or tapeworms, including species such as Taenia, Echinococcus, and Dipylidium caninum, which are common in livestock and companion animals. These tapeworm infections can lead to nutrient malabsorption, weight loss, and overall poor health in animals. Praziquantel’s targeted action against tapeworms helps eliminate these parasites efficiently.

3. Comparison of Antiparasitic Activity

Praziquantel is widely regarded for its rapid and effective antiparasitic action against trematodes and cestodes. Compared to other antiparasitic agents, Praziquantel provides comprehensive control over both flukes and tapeworms with a single dose, which simplifies treatment protocols. Its quick action and high efficacy make it particularly valuable in field conditions, reducing the need for multiple doses and minimizing stress for animals, which is beneficial in both intensive and extensive farming environments.

4. Application Fields

Praziquantel is extensively used in veterinary medicine for the prevention and treatment of parasitic infections in livestock and companion animals.

•Veterinary Use: Praziquantel is primarily used for the treatment of trematode and cestode infections in livestock, including cattle, sheep, goats, and swine. It is also used in companion animals like dogs and cats to treat tapeworm infections. The antiparasitic properties of Praziquantel help improve animal health, growth, and productivity by effectively eliminating parasites that affect nutrient absorption and overall well-being.

•Comprehensive Parasite Management: Due to its broad-spectrum efficacy, Praziquantel is ideal for integrated parasite management programs, where it can be used alongside other anthelmintics to provide comprehensive control over internal parasites.

1. Shelf Life

Praziquantel has a shelf life of 2 years when stored under recommended conditions. During this period, the product retains its quality, potency, and stability, ensuring consistent efficacy in veterinary applications for treating parasitic infections.

2. Testing Indicators and Standards

2.1 Appearance

Praziquantel should appear as a white to off-white crystalline powder. Any noticeable deviation from this appearance may indicate potential quality concerns, serving as an essential quality control measure.

2.2 Identification

The identity of Praziquantel is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC) and Infrared Spectroscopy (IR). These tests verify retention time and other chemical properties to ensure product purity and authenticity.

2.3 pH Value

The pH of a 1% solution of Praziquantel in water should fall within the specified range according to product standards. Maintaining this pH range is crucial for product stability and optimal biological activity in veterinary applications.

2.4 Specific Absorbance

At 263 nm, the specific absorbance of Praziquantel should meet the required range to confirm product purity and compliance with quality standards.

2.5 Light Absorbing Impurities

Impurities that absorb light at 400 nm should be controlled within specified limits to ensure stability. Managing these impurities helps maintain Praziquantel’s efficacy and consistency in veterinary use over time.

2.6 Related Substances Content

Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and effectiveness of Praziquantel in treating parasitic infections.

2.7 Heavy Metals Content

The heavy metals content in Praziquantel should not exceed 10 ppm. Keeping heavy metal levels low is essential for product safety, minimizing potential risks to animal health.

2.8 Water Content

Water content should be controlled between 0.5% and 1.5%. Proper moisture levels are critical to preserving the stability and quality of Praziquantel, preventing degradation over time.

2.9 Residue on Ignition (Ash Content)

The ash content, or residue on ignition, should not exceed 0.1%. Low ash levels reflect high product purity, indicating minimal unwanted inorganic contaminants.

2.10 Content Determination

The active content of Praziquantel should fall between 98.0% and 102.0%. Meeting this specification ensures consistent effectiveness in veterinary treatments, providing reliable antiparasitic action against trematodes and cestodes in livestock and companion animals.

1. Packaging

Praziquantel is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging safeguards the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Praziquantel during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and making inventory management more efficient.

2. Transportation Modes

2.1 Express Shipping

For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These trusted carriers provide rapid delivery to meet urgent customer needs while preserving product integrity throughout transit.

2.2 Air and Sea Freight

For bulk orders, we offer both air and sea freight options to accommodate various customer needs. Air freight provides faster delivery for large quantities but may involve higher costs. Sea freight is a more economical option for larger shipments, though it requires a longer transit time. Customers can choose the transportation method that best aligns with their order size, budget, and delivery timeline.

3. Delivery Time

Once payment is received, Praziquantel orders are typically processed and dispatched within 2–3 business days. This swift turnaround enables us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.

Q1: How can I place an order for Praziquantel?

A: To place an order, please contact our customer service team through any of the following methods:

•WeChat: +86-18663729963, +86-13589106478

•Skype: sunnylee886

•Email: maggie@hope-biotech.com, sunny@hope-biotech.com

•Mobile: +86-18663729963, +86-13589106478

Our team is available to guide you through the ordering process and answer any questions you may have.

Q2: What is the minimum order quantity (MOQ) for Praziquantel?

A: The standard MOQ for Praziquantel is 1 kg. If you need a different quantity, please get in touch with us, and we will do our best to accommodate your specific needs.

Q3: What certifications does your company hold for Praziquantel?

A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and superior manufacturing practices. These certifications demonstrate our commitment to producing Praziquantel at the highest standards for quality, safety, and reliability in veterinary and pharmaceutical applications.

Q4: What are the main applications of Praziquantel?

A: Praziquantel is widely used as an anthelmintic agent to treat parasitic infections, particularly schistosomiasis and tapeworm infestations, in both veterinary and human medicine. It is effective against a variety of flatworms, including Schistosoma species, liver flukes, and tapeworms, making it a versatile choice for managing parasitic diseases in animals and humans.

Q5: How should Praziquantel be stored?

A: Praziquantel should be stored in a cool, dry place, away from direct sunlight and moisture. Optimal storage conditions help maintain the product’s potency and efficacy over time. Keep the container tightly sealed when not in use, and store it out of reach of children and animals.

Q6: Is Praziquantel safe for use in different animal species?

A: Praziquantel is generally safe when used in accordance with recommended dosages for various animal species, including cattle, horses, dogs, and cats. However, dosage and administration should be guided by a veterinarian to ensure safety and efficacy.

Q7: Can Praziquantel be combined with other antiparasitic medications?

A: Yes, Praziquantel is often combined with other antiparasitic agents, such as ivermectin or pyrantel, in combination formulations to broaden the spectrum of parasitic coverage. Consult your veterinarian for guidance on combination therapies suitable for your specific application.

Q8: What is the typical shelf life of Praziquantel?

A: Praziquantel has a shelf life of approximately 2 years when stored under appropriate conditions. Regular quality checks are performed to ensure product stability and efficacy throughout its shelf life.

Q9: What testing standards does your Praziquantel meet?

A: Our Praziquantel undergoes rigorous quality control, including High-Performance Liquid Chromatography (HPLC) and purity testing, to confirm compliance with international quality standards. We provide a Certificate of Analysis (CoA) with each batch, detailing purity, potency, and safety indicators.