1. Name and Synonyms

The product is officially named Tilmicosin Phosphate and is commonly recognized by this name across veterinary and pharmaceutical contexts. This standardized name ensures clear identification for various applications.

2. Chemical Identification

Tilmicosin Phosphate is identified by the CAS number 137330-13-3, serving as a unique identifier within the veterinary and pharmaceutical industries. This CAS number aids in precise tracking in research, production, and quality control processes.

3. Appearance and Physical Properties

Tilmicosin Phosphate typically appears as a pale yellow to yellow crystalline powder. This characteristic supports quality control and product identification during manufacturing and distribution.

4. Purity and Solubility

Tilmicosin Phosphate has a high purity level of ≥ 98%, ensuring reliable performance in veterinary applications. It is slightly soluble in water and highly soluble in organic solvents such as methanol and acetone, providing versatility in formulations for injectable and oral solutions.

5. Molecular Structure

The molecular formula of Tilmicosin Phosphate is C₄₆H₈₀N₂O₁₃ • H₃PO₄, with a molecular weight of approximately 967.1 g/mol. This structure enables it to inhibit bacterial protein synthesis effectively, making Tilmicosin Phosphate an optimal choice for managing respiratory infections in livestock.

1. Antibiotic Type

Tilmicosin Phosphate is a macrolide antibiotic specifically formulated to target respiratory pathogens in livestock. It functions by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, effectively stopping bacterial growth and replication. This targeted mechanism makes Tilmicosin Phosphate particularly effective for treating respiratory infections in cattle, swine, and poultry, especially in intensive farming environments where respiratory disease management is crucial.

2. Antibacterial Spectrum

2.1 Gram-Negative Bacteria

Tilmicosin Phosphate is highly effective against key Gram-negative respiratory pathogens, including Mannheimia haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae. These bacteria are common culprits in respiratory diseases such as Bovine Respiratory Disease (BRD) in cattle and respiratory infections in swine. Tilmicosin Phosphate’s efficacy against these pathogens makes it a valuable tool for respiratory disease management in livestock.

2.2 Gram-Positive Bacteria

Tilmicosin Phosphate also exhibits substantial activity against specific Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus suis, which are sometimes involved in respiratory and systemic infections. This additional activity enhances Tilmicosin Phosphate’s utility in treating mixed bacterial infections, offering comprehensive respiratory disease management in livestock.

2.3 Mycoplasmas

Tilmicosin Phosphate is effective against Mycoplasma species, including Mycoplasma hyopneumoniae in swine and Mycoplasma bovis in cattle, both of which are known to cause chronic respiratory infections. The effectiveness of Tilmicosin Phosphate against Mycoplasma is a significant advantage, as these pathogens are often resistant to many other antibiotic classes.

3. Comparison of Antibacterial Activity

Tilmicosin Phosphate is well-regarded for its long-acting antibacterial effects and targeted action against both Gram-negative and certain Gram-positive bacteria, as well as Mycoplasma species. Unlike some other antibiotics, Tilmicosin Phosphate can be administered as a single dose with prolonged activity, making it practical and efficient for field use. Its extended duration of action reduces the need for frequent dosing and minimizes animal handling, which is beneficial in intensive farming operations where reducing stress is essential.

4. Application Fields

Tilmicosin Phosphate is widely employed in veterinary medicine for the prevention and treatment of respiratory infections in livestock, particularly in cattle, swine, and poultry. It is especially useful in managing diseases like Bovine Respiratory Disease (BRD) in cattle and respiratory infections in swine herds, which can significantly affect animal productivity. Tilmicosin Phosphate’s single-dose efficacy and long-lasting effects make it a preferred choice in intensive farming environments, where effective disease control, reduced handling, and improved animal welfare are priorities.

1. Shelf Life

Tilmicosin Phosphate has a shelf life of 2 years when stored under recommended conditions. During this period, the product maintains its quality, potency, and stability, ensuring consistent efficacy in veterinary applications.

2. Testing Indicators and Standards

2.1 Appearance

Tilmicosin Phosphate should appear as a pale yellow to yellow crystalline powder. Any noticeable deviation from this appearance may indicate potential quality issues, serving as an important quality control parameter.

2.2 Identification

The identity of Tilmicosin Phosphate is confirmed through analytical methods such as High-Performance Liquid Chromatography (HPLC). These tests verify retention time and other chemical properties to ensure product purity and authenticity.

2.3 pH Value

The pH of a 1% aqueous solution of Tilmicosin Phosphate should range between 7.0 and 9.0. Maintaining this pH range is crucial for product stability and optimal biological activity in veterinary applications.

2.4 Specific Absorbance

At 280 nm, the specific absorbance of Tilmicosin Phosphate should meet the required range to confirm product purity and compliance with quality standards.

2.5 Light Absorbing Impurities

Impurities that absorb light at 400 nm should be controlled within specified limits. Managing these impurities helps ensure Tilmicosin Phosphate’s stability and consistent performance in veterinary use.

2.6 Related Substances Content

Strict limits are set for related substances, with total impurities not exceeding 1.0%. This control ensures high purity and efficacy of Tilmicosin Phosphate in treating respiratory infections in livestock.

2.7 Heavy Metals Content

The heavy metals content in Tilmicosin Phosphate should not exceed 10 ppm. Keeping heavy metal levels low is essential for product safety, minimizing potential risks to animal health.

2.8 Water Content

Water content should be controlled between 1.0% and 2.0%. Proper moisture levels help preserve the stability and quality of Tilmicosin Phosphate, preventing degradation over time.

2.9 Residue on Ignition (Ash Content)

The ash content, or residue on ignition, should not exceed 0.2%. Low ash levels indicate high product purity, free from unwanted inorganic contaminants.

2.10 Content Determination

The active content of Tilmicosin Phosphate should fall between 98.0% and 102.0%. Meeting this specification ensures the product’s effectiveness in veterinary treatments, providing reliable antibacterial action against respiratory pathogens in livestock.

1. Packaging

Tilmicosin Phosphate is securely packaged in fiber drums, available in standard sizes of 15 kg/drum and 25 kg/drum. This packaging protects the product from environmental factors such as moisture, light, and oxidation, ensuring the stability and quality of Tilmicosin Phosphate during storage and transportation. The fiber drums are designed for easy handling, optimizing logistics and making inventory management more efficient.

2. Transportation Modes

2.1 Express Shipping

For smaller or urgent orders, we offer express shipping through reputable international carriers, including DHL, TNT, and FedEx. These trusted carriers provide rapid delivery to meet urgent customer needs while maintaining product integrity throughout transit.

2.2 Air and Sea Freight

For bulk orders, we offer both air and sea freight options to accommodate different customer needs. Air freight provides faster delivery for large quantities but may incur higher costs. Sea freight is a more economical option for larger shipments, though it requires a longer transit time. Customers can select the transportation method that best suits their order size, budget, and delivery requirements.

3. Delivery Time

Once payment is received, Tilmicosin Phosphate orders are typically processed and dispatched within 2–3 business days. This quick turnaround allows us to meet urgent customer demands, enhancing customer satisfaction and reinforcing trust in our reliable and efficient service.

Q1: How can I place an order for Tilmicosin Phosphate？

A: To place an order, please contact our customer service team directly through any of the following methods:

•WeChat: +86-18663729963, +86-13589106478

•Skype: sunnylee886

•Email: maggie@hope-biotech.com, sunny@hope-biotech.com

•Mobile: +86-18663729963, +86-13589106478

Our team will assist you with the ordering process and provide answers to any questions you may have.

Q2: What is the minimum order quantity (MOQ) for Tilmicosin Phosphate?

A: Our standard MOQ for Tilmicosin Phosphate is 0.5 kg. However, if you need a different quantity, please contact us, and we will do our best to accommodate your specific requirements.

Q3: What certifications does your company hold for Tilmicosin Phosphate?

A: Our production facility is certified with GMP and ISO 9001 standards, ensuring rigorous quality control and superior manufacturing processes. We also hold FSC and CEP certifications, confirming our commitment to high standards in the production of Tilmicosin Phosphate for quality, safety, and reliability.

Q4: What is the primary use of Tilmicosin Phosphate in veterinary medicine?

A: Tilmicosin Phosphate is a macrolide antibiotic widely used in veterinary medicine to treat respiratory infections in livestock, particularly in cattle, swine, and poultry. It is effective against pathogens like Mannheimia haemolytica, Pasteurella multocida, and Mycoplasma species, making it ideal for managing respiratory diseases in intensive farming environments.

Q5: How should Tilmicosin Phosphate be stored?

A: Tilmicosin Phosphate should be stored in a cool, dry place, away from direct sunlight and moisture. Proper storage conditions are essential to maintain the product’s stability, quality, and effectiveness over its shelf life.

Q6: What is the shelf life of Tilmicosin Phosphate?

A: Tilmicosin Phosphate has a shelf life of 2 years when stored under recommended conditions. This ensures that the product remains stable and effective during this period.

Q7: Is Tilmicosin Phosphate effective for single-dose administration?

A: Yes, Tilmicosin Phosphate has a long-acting formulation, which allows for single-dose administration in many cases, reducing the need for repeated dosing. This property makes it convenient for use in large-scale livestock operations by minimizing handling and stress on animals.

Q8: Is Tilmicosin Phosphate safe for use in all types of livestock?

A: Tilmicosin Phosphate is widely used in cattle, swine, and poultry for managing respiratory infections. However, dosage and administration guidelines should be strictly followed as directed by a veterinarian, as the drug may have specific usage restrictions in certain species.

Q9: Can I request a Certificate of Analysis (CoA) for Tilmicosin Phosphate?

A: Yes, we provide a Certificate of Analysis (CoA) for each batch of Tilmicosin Phosphate upon request. The CoA includes detailed information on purity, potency, and compliance with quality standards, ensuring transparency and product quality assurance.

Q10: How is Tilmicosin Phosphate administered?

A: Tilmicosin Phosphate is typically administered either as an injectable solution or via feed and water formulations. The exact method of administration depends on the type of livestock and the specific condition being treated.